Over four decades ago, it was discovered that high-frequency stimulation of the dentate gyrus induces long-term potentiation (LTP) of synaptic transmission. LTP is believed to underlie how we process and code external stimuli before converting it to salient information that we store as 'memories'. It has been shown that rats performing spatial learning tasks display theta-frequency (3-12 Hz) hi...

BACKGROUND Although single- and paired-pulse (sp/pp) transcranial magnetic stimulation (TMS) studies are considered minimal risk in adults and children, the safety profile for theta-burst TMS (TBS) is unknown. OBJECTIVE In this comparative analysis, we explored the rate, severity, and specific symptoms of TMS-related adverse effects (AEs) between sp/ppTMS and TBS in subjects between ages 6 an...

Theta-burst stimulation (TBS) over human primary motor cortex evokes plasticity and metaplasticity, the latter contributing to the homeostatic balance of excitation and inhibition. Our knowledge of TBS-induced effects on primary somatosensory cortex (SI) is limited, and it is unknown whether TBS induces metaplasticity within human SI. Sixteen right-handed participants (6 females, mean age 23 yr...

This study investigated the impact of different light curing units (LCUs) for the polymerization of adhesive system visio.link (VL) on the tensile bond strength (TBS) of different PEEK compositions. For TBS measurements, 216 PEEK specimens with varying amounts of TiO₂ (PEEK/0%, PEEK/20%, PEEK/>30%) were embedded, polished, air abraded (Al₂O₃, 50 µm, 0.4 MPa), conditioned using VL, and polymeriz...

In the present study, we perform molecular dynamic simulations to investigate the compression response and atomistic deformation mechanisms of twinned nanospheres. The relationship between load and compression depth is calculated for various twin spacing and loading directions. Then, the overall elastic properties and the underlying plastic deformation mechanisms are illuminated. Twin boundarie...

Objectives: The aim of this study was to compare the microtensile bond strengths (µ TBS) of three core materials with one lithium disilicate reinforced ceramic using two resin cements. Methods: Three core materials (Nulite F® (Biodental Technologies), Filtek Z250® (3M-ESPE), Prettau-Anterior® (Zirkonzhan, Germany)) were prepared as blocks (10×10×4 mm3) according...

Relevance of the topic.  A person’s daily life is full stress and tension, often current age called era stress. The impact in professional activities becoming one most relevant topics. One these includes ambulance physicians [1], [2]. Recent during a coronavirus pandemic sensitive pressing issues. Ambulances are currently working particularly difficult conditions, facing non-standard situa...

This paper formalizes the concept of threshold blind signatures (TBS) that bridges together properties of the two well-known signature flavors, blind signatures and threshold signatures. Using TBS users can obtain signatures through interaction with t-out-of-n signers without disclosing the corresponding message to any of them. Our construction is the first TBS scheme that achieves security in ...

BACKGROUND Traditional Botanical Supplement-101 (TBS-101) is a newly developed proprietary botanical agent containing seven standardized botanical extracts, including: Panax ginseng, cranberry, green tea, grape skin, grape seed, Ganoderma lucidum and chamomile. Each of the components has been consumed either in the regular diet or as natural supplement. When used as a single agent, each of thes...

The fasciolicides tribromsalan (TBS), oxyclozanide (OCZ) and bromofenofos (BFF) were orally administered to three lactating cows. The concentrations of TBS, OCZ and the BFF metabolite dephosphate bromofenofos (DBFF) in plasma, and the excretion of these compounds in milk were determined by high-performance liquid chromatography. In plasma, the concentrations of TBS, OCZ and DBFF reached maximum...