Space flight studies using the Animal Enclosure Module (AEM) make it possible to investigate the role of microgravity on animal physiology and behavior. In this study, we compared the health and well-being of mice housed at different densities in AEM simulators (AEMS), to vivarium shoebox (control) cages (VSBC). A stress assessment battery (SAB) of measures was developed to evaluate mouse healt...

Background of study: Sepsis is a life-threatening medical condition characterized by an overwhelming infection and the body’s inflammatory response to infection. Thus, it is a potentially life-threatening condition that requires a medical emergency. Objective: This was designed to evaluate the usefulness of C-Reactive Protein (CRP) in the management of individuals being treated for various infe...

INTRODUCTION Regarding the inflammatory mechanisms involved in ischemic heart disease, currently the leukocyte count is the subject of studies related to its association with the prognosis and mortality of ST segment elevation myocardial infarction (STEMI). Our aim is correlate the leukocyte count rise with the size of STEMI, evaluated with the area under the curve (AUC) and the peak of necrosi...

Objectives: Total leukocyte count, a marker of inflammation has long been reported to be related with coronary artery disease (CAD). Recently, differenttial leukocyte count and elevated neutrophil to lymphocyte ratio (N/L) has been shown to indicate an increased long-term risk of mortality in patients with stable CAD, myocardial infarction and undergoing cardiovascular surgery. These studies of...

OBJECTIVE To determine the frequency and severity of leucopenia during antiviral treatment in patients with hepatitis C and the effectiveness of G-CSF (Granulocyte-Colony Stimulating Factor) in its management. STUDY DESIGN An observational study. PLACE AND DURATION OF STUDY Shafi Clinic, Rawalpindi, from July 2005 to July 2007. METHODOLOGY Patients with Polymerase Chain Reaction (PCR) pos...

Soluble IL-2 receptor (sIL-2R), total protein, uric acid, glucose, aspartate aminotransferase (AST) and lactate dehydrogenase (LD) levels were analyzed in 153 (19 cytology(+), 134 cytology(-)) pairs of CSF and serum samples and the data were compared with the results of cytologic examination to find new CSF markers of CNS involvement in 77 patients with acute lymphoblastic leukemia (ALL). The C...

Objective: The primary objective of this study was to investigate the correlation between Total Leukocyte Count (TLC) and C-Reactive Protein (CRP) levels in paediatric bronchiolitis patients assess prognostic significance these markers disease severity patient outcomes. Study Design: A retrospective correlational conducted using records from a six-month period analyze relationship TLC CRP patie...

Background: The peripheral leucocyte count is an important predictor of morbidity and mortality. Hence, host and environmental factors influencing the peripheral leukocyte count are of interest. The influence of smoking on Total Leucocyte Count and Differential Leucocyte Count was investigated. Aims & Objective: To see the influence of smoking on Total Leucocyte Count (TLC) and Differential Leu...