An oral sustained-release floating tablet formulation of metformin HCl was designed and developed. Effervescence and swelling properties were attributed on the developed tablets by sodium bicarbonate and HPMC-PEO polymer combination, respectively. Tablet composition was optimized by response surface methodology (RSM). Seventeen (17) trial formulations were analyzed according to Box-Behnken desi...

Introduction: Environmental features of the city of Zenica cause an increased risk of air pollutionrelated diseases in preschool children. Goal: The purpose of this paper is to examine a correlation between the air pollution-related diseases in preschool children and the average values of monthly concentration of sulfur dioxide (SO2) and total range of floating particles in the area of the city...

The present investigation is concerned about the development of floating bioadhesive drug delivery system of venlafaxine hydrochloride which after oral administration exhibits a unique combination of floating and bioadhesion to prolong gastric residence time and increase drug bioavailability within the stomach. The floating bioadhesive tablets were prepared by the wet granulation method using d...

Floating point unit is commonly used in computers. However, the arithmetic logic unit (ALU) for floating point operations such as addition or subtraction is complicated. Moreover, many floating point ALUs are designed to operate in many clock cycles. Thus, its speed are varied depend on the number of clock cycle. However, in many field, circuits with fix delay time are preferred. This work prop...

The floating photovoltaic system is a new concept in energy technology to meet the needs of our time. The system integrates existing land based photovoltaic technology with a newly developed floating photovoltaic technology. Because module temperature of floating PV system is lower than that of overland PV system, the floating PV system has 11% better generation efficiency than overland PV syst...

Chitosan (CS) floating lyophilized formulations (L) for gastric drug delivery of acyclovir (ACV) have been developed. The freeze-dried formulations were obtained from acidic aqueous suspensions prepared with different ACV/CS ratios. No changes in ACV crystallinity were observed during X-ray diffraction powder studies as a consequence of the manufacturing process. Considering that fed and fasted...

Floating-point computations are usually performed with fixed precision: the machine used may have “single” or “double” precision floating-point hardware, or on small machines fixed-precision floating-point operations may be implemented by software or firmware. Most high-level languages support only a small number of floating-point precisions, and those which support an arbitrary number usually ...

A review of the research carried out at the University of Michigan and elsewhere on the use of time-domain panel methods to compute the hydrodynamic forces acting on floating bodies is presented. Both linear and fully nonlinear computational techniques are presented. The linear problem is solved using a time-domain Green function approach. The fully nonlinear computations are done using an Eule...

The purpose of the study was to prepare and evaluate clarithromycin (CLA) floating tablets using experimental mixture design for treatment of Helicobacter pylori provided by prolonged gastric residence time and controlled plasma level. Ten different formulations were generated based on different molecular weight of hypromellose (HPMC K100, K4M, K15M) by using simplex lattice design (a sub-class...

This project explores the use of machine learning techniques to accurately predict travel times in city streets and highways using floating car data (location information of user vehicles on a road network). The aim of this report is twofold, first we present a general architecture of solving this problem, then present and evaluate few techniques on real floating car data gathered over a month ...