objective(s):hyperglycemia mediated oxidative stress plays a key role in the pathogenesis of diabetic complications like nephropathy. in the present study, we evaluated the effect of ethanolic extract of ensete superbum seeds (esse) on renal dysfunction and oxidative stress in streptozotocin-induced diabetic rats. materials and methods:glucose, hba1c, total protein, albumin, renal function mark...

Reactive oxygen species (ROS) have been implicated in a variety of age-related diseases, including multiple cardiovascular disorders. However, translation of ROS scavengers (antioxidants) into the clinic has not been successful. These antioxidants grossly reduce total levels of cellular ROS including ROS that participate in physiological signaling. In this review, we challenge the traditional a...

natural antioxidants have an important role in the prevention of many age-related diseases and promotion of health. among natural antioxidants from plants, flavonoids and other phenolic compounds are potent antioxidants and chelating agents. moringa peregrina (forssk.) fiori (moringaceae) is a small desert tree distributed from tropical africa to east india. moringa tree is also growing in sout...

This study aimed to compare the antioxidant content and antioxidant capacity of pulp and peel of two varieties of pomelo fruit (Tambun White and Tambun Pink). Antioxidants including total phenolic content, total flavonoid content and ascorbic acid content were determined using Folin-Ciocalteu reagent assay, aluminium chloride colorimetric assay and AOAC method, respectively. Antioxidant capacit...

in this study, the essential oil obtained by hydrodistillation of the seeds of vitex pseudo-negundo (verbenaceae), growing wild in sabzevar, khorasan razavi province, iran, were analyzed by gc and gc/ms. the yield of total volatiles was 0.8% (w/w). thirty-seven compounds representing 92.4% of the seed oil were identified. the main components of the oil were hexadecanoic acid (8.0%), elemol (7.0...

Ultrasound-assisted micellar extraction of phenolic antioxidants from spices has been developed for the first time. The effect of the surfactant nature and its concentration on the extraction efficiency has been evaluated. Electrogenerated hexacyanoferrate(III) ions have been used as coulometric titrants owing to their selectivity towards phenolic antioxidants. The best recovery of phenolic ant...

INTRODUCTION Oxidative stress and antioxidants play an important role in the pathogenesis of inflammatory disease, including chronic periodontitis (CP). Saliva contains enzymatic (glutathione peroxidase - GPx, superoxide dismutase - SOD, etc.) and non-enzymatic (albumin - ALB, uric acid - UA, glutathione, etc.) antioxidants. OBJECTIVE The aims of this study were to investigate: a) level of SO...

Antioxidant treatment has previously been shown to be neuroprotective in experimental bacterial meningitis. To obtain quantitative evidence for oxidative stress in this disease, we measured the major brain antioxidants ascorbate and reduced glutathione, and the lipid peroxidation endproduct malondialdehyde in the cortex of infant rats infected with Streptococcus pneumoniae. Cortical levels of t...

Objectives: The study aims to estimate the changes in the serum levels of lipid peroxidation product malondialdehyde (MDA), non-enzymatic antioxidants: vitamin A, E and C and erythrocyte enzymatic antioxidants: superoxide dismutase (SOD) and catalase(CAT) in chronic alcoholic liver disease. Background: Alcohol consumption accounts for about 50% of patients death from end stage liver disease in ...

OBJECTIVE To investigate if blood Cu++/Zn++ superoxide dismutase, glutathione peroxidase, catalase, and total plasma antioxidant activities could be markers of biological activity resulting from exposure to respirable coal mine dust in active miners, and of pneumoconiosis in retired miners. METHODS Blood samples were randomly obtained from active surface workers (n = 30) and underground miner...