background: diabetes mellitus is associated with chronic changes in peripheral arteries because of oxidative stress and insufficient antioxidative defense mechanism. omega-3 fatty acid supplementation could be effective in some diabetes complications; however, polyunsaturated fatty acids may increase lipid peroxidation. this study aimed to determine whether eicosapentaenoic acid alone or in con...

background: there is growing evidence that damage to spermatozoa by reactive oxygen species (ros) play a key role in male infertility. objective: the aim of the present study was to assess the antioxidant status of seminal plasma by measuring total antioxidant capacity (tac) and activities of catalase and superoxide dismutase (sod) in men with asthenozoospermia, asthenoteratozoospermia and olig...

OBJECTIVE To determine the association between oxidative stress parameters with periodontal disease, bleeding, and the presence of different periodontal bacteria. METHODS A cross-sectional study in a sample of eighty-six patients, divided into three groups depending on their periodontal status. Thirty-three with chronic periodontitis, sixteen with gingivitis, and thirty-seven with periodontal...

OBJECTIVE To investigate effects of glucose excursion on the oxidative/antioxidative system in subjects with different types of glucose regulation. METHODS A total of 30 individuals with normal glucose regulation (NGR), 27 subjects with impaired glucose regulation (IGR) and 27 subjects with newly diagnosed type 2 diabetes mellitus (T2DM) were selected and recruited for 3 days' continuous gluc...

OBJECTIVE To investigate the potential role of peroxiredoxin 1 in lipopolysaccharide (LPS) induced acute lung injury (ALI) in mice and the possible mechanism. MATERIALS AND METHODS Male Prdx1 knockout mice (Prdx1 (-/-)) and C57BL/6 wild-type mice with the same genetic background were used in this experiment. Primary culture of peritoneal macrophages was performed to measure the level of react...

To investigate the effects of colchicine on left ventricular (LV) function and hypertrophy (LVH) of rats subjected to constriction of transverse aorta (TAoC), we evaluated SO (sham operated, vehicle; n = 25), SO-T (sham operated, colchicine 0.4 mg/kg body wt ip daily; n = 38), TAoC (vehicle; n = 37), and TAoC-T (TAoC, colchicine; n = 34) on the 2nd, 6th, and 15th day after surgery. Colchicine a...

background: fat-rich diet may alter oocyte development and maturation and embryonic development by inducing oxidative stress (os) in follicular environment. objective: to investigate the relationship between fat intake and oxidative stress with oocyte competence and embryo quality. materials and methods: in observational study follicular fluid was collected from 236 women undergoing assisted re...

background: the role of attenuation in antioxidant capacity or expansion of pro-oxidant/oxidant is well known for the development of stress oxidative. the aim of this study was to evaluate the plasma antioxidant capacity along with uric acid in patients with diabetic nephropathy (dn+) and without diabetic nephropathy (dn-). materials and methods: the research population included 88 patients wit...

ethanolic extract of leaves of elaeocarpus ganitrus was analyzed for their total antioxidant capacity, reducing power, metal chelating, abts+ (2, 2-azinobis-(3-ethylbenzothiazoline-6-sulphonate) radical scavenging and hydroxyl radical scavenging activities. the extract at 500 ?g/ml showed maximum iron chelating activity (76.70%) followed by the scavenging of the abts+ radical (55.77%) at the sa...