The present study has investigated the cytoprotective effects of chlorophyllin in tobacco induced chromosomal aberrations in bone marrow of rats. Chromosomal aberrations per cell and percent aberrant cells were observed to calculate genotoxic action of tobacco. Oral treatment with different doses of chln was able to reduce chromosomal aberrations significantly at the pre-treatment level and con...

The potential of tobacco waste as a viable source of medicinally important flavonoids like rutin has been investigated. Three flavonoids, apigenin, quercetin and rutin, have been isolated from waste tobacco leaves, and their identities have been confirmed by UV-visible, 1H-NMR and 13C-NMR spectroscopy. By using analytical HPLC, the amount of rutin present in the tobacco leaves, before and after...

Tobacco smoking is a global problem associated with the occurrence of many systemic diseases and tumors. Oral cavity tumors are common tobacco-related cancers, and of all the anatomical structures that are exposed to the effects of smoking, the oral cavity remains the least-explored area. Changes that occur in the biology of oral epithelial keratinocytes under the influence of the components of...

When tobacco BY-2 cells were treated with 60 microg/mL MC-RR for 5d, time-dependent effects of MC-RR on the cells were observed. Morphological changes such as abnormal elongation, evident chromatin condensation and margination, fragmentation of nucleus and formation of apoptotic-like bodies suggest that 60 microg/mL MC-RR induced rapid apoptosis in tobacco BY-2 cells. Moreover, there was a sign...

The replication-associated proteins encoded by Cucumber mosaic virus (CMV), the 1a and 2a proteins, were detected by immunogold labeling in two host species of this virus, tobacco (Nicotiana tabacum) and cucumber (Cucumis sativus). In both hosts, the 1a and 2a proteins colocalized predominantly to the vacuolar membranes, the tonoplast. While plus-strand CMV RNAs were found distributed throughou...

Topping stage of tobacco is a key time for development of agriculture measures to promote the quality of leaves. In order to investigating influence of topping timing and suckericide content on tobacco leaf, a factorial experiment on the basis of RCB design with 3 replications was conducted in 2011 at the Tobacco Research Farm of Isfahan. Treatments were including topping time (T1: t...