Background and objectives: The cholinergic deficit correlates with the severity of Alzheimer’s disease. The cholinergic function can be improved by AChE inhibitors blocking this key enzyme in the breakdown of acetylcholine. Based on traditional medicine, during two last decades the use of herbal medicinal substances in dementia therapy has been studied. Nardostachys jataman...

Two new garcinia acid derivatives, 2-(butoxycarbonylmethyl)-3-butoxycarbonyl-2-hydroxy-3-propanolide and 1',1"-dibutyl methyl hydroxycitrate, were isolated from the fruits of Garcinia atroviridis guided by TLC bioautography against the fungus Cladosporium herbarum. The structures of these compounds were established by spectral analysis. The former compound represents a unique beta-lactone struc...

The search for natural sources of molecules that exhibit biological activity has intensified in the last 20 years. The andiroba (Carapa guianensis) oil is known for its medicinal actions [1], and biological activities, among them the antioxidant action [2]. The use of traditional techniques for the determination of antioxidant activity in vegetable oils faces strong competition from modern tech...

Abstract Pseudomonas azotoformans known for the benefit on agriculture area as soil fertility enhancer. UICC B-91 was successfully isolated from tissues of N. altissima which traditionally treating infectious diseases. Therefore, endophytic P. might contain antimicrobial compound. This research aims exploring activities several extracts against pathogenic microbes. Isolates were extracted with ...