نتایج جستجو برای: tissue tropism

تعداد نتایج: 921469  

2016
Hicham El Costa Jordi Gouilly Jean-Michel Mansuy Qian Chen Claude Levy Géraldine Cartron Francisco Veas Reem Al-Daccak Jacques Izopet Nabila Jabrane-Ferrat

The outbreak of the Zika Virus (ZIKV) and its association with fetal abnormalities have raised worldwide concern. However, the cellular tropism and the mechanisms of ZIKV transmission to the fetus during early pregnancy are still largely unknown. Therefore, we ex vivo modeled the ZIKV transmission at the maternal-fetal interface using organ culture from first trimester pregnancy samples. Here, ...

Journal: :Translational and regulatory sciences 2023

Advances in gene therapy have led to a wide range of products. Hence, it is challenging use standard non-clinical safety tests, which are typically used evaluate chemically synthesized Therefore, case-by-case evaluation based on the unique characteristics each product necessary. In Japan, fundamental considerations for evaluating products outlined “Ensuring Quality and Safety Gene Therapy Produ...

Journal: :Symmetry 2021

Tropism, or asymmetry, of facet joints in the cervical spine has been found to be related degenerative changes and discs. Clinicians often assume that differences segmental mobility are tropism. The aims this study were determine relationship between asymmetry sub-axial (1) (2) spinal levels perceived by therapists have limited mobility. Eighteen participants with idiopathic neck pain had MRIs ...

2016
Alejandro Manzano-Marín Amparo Latorre

Genome reduction is pervasive among maternally-inherited endosymbiotic organisms, from bacteriocyte- to gut-associated ones. This genome erosion is a step-wise process in which once free-living organisms evolve to become obligate associates, thereby losing non-essential or redundant genes/functions. Serratia symbiotica (Gammaproteobacteria), a secondary endosymbiont present in many aphids (Hemi...

2014
Agustín Enrique Ure Ola Forslund

The novel human papillomavirus type 154 (HPV154) was characterized from a wart on the crena ani of a three-year-old boy. It was previously designated as the putative HPV type FADI3 by sequencing of a subgenomic FAP amplicon. We obtained the complete genome by combined methods including rolling circle amplification (RCA), genome walking through an adapted method for detection of integrated papil...

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