نتایج جستجو برای: tissue tropism
تعداد نتایج: 921469 فیلتر نتایج به سال:
The outbreak of the Zika Virus (ZIKV) and its association with fetal abnormalities have raised worldwide concern. However, the cellular tropism and the mechanisms of ZIKV transmission to the fetus during early pregnancy are still largely unknown. Therefore, we ex vivo modeled the ZIKV transmission at the maternal-fetal interface using organ culture from first trimester pregnancy samples. Here, ...
Advances in gene therapy have led to a wide range of products. Hence, it is challenging use standard non-clinical safety tests, which are typically used evaluate chemically synthesized Therefore, case-by-case evaluation based on the unique characteristics each product necessary. In Japan, fundamental considerations for evaluating products outlined “Ensuring Quality and Safety Gene Therapy Produ...
Tropism, or asymmetry, of facet joints in the cervical spine has been found to be related degenerative changes and discs. Clinicians often assume that differences segmental mobility are tropism. The aims this study were determine relationship between asymmetry sub-axial (1) (2) spinal levels perceived by therapists have limited mobility. Eighteen participants with idiopathic neck pain had MRIs ...
Genome reduction is pervasive among maternally-inherited endosymbiotic organisms, from bacteriocyte- to gut-associated ones. This genome erosion is a step-wise process in which once free-living organisms evolve to become obligate associates, thereby losing non-essential or redundant genes/functions. Serratia symbiotica (Gammaproteobacteria), a secondary endosymbiont present in many aphids (Hemi...
The novel human papillomavirus type 154 (HPV154) was characterized from a wart on the crena ani of a three-year-old boy. It was previously designated as the putative HPV type FADI3 by sequencing of a subgenomic FAP amplicon. We obtained the complete genome by combined methods including rolling circle amplification (RCA), genome walking through an adapted method for detection of integrated papil...
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