Pseudomonas aeruginosa and Acinetobacter baumannii are common nosocomial pathogens, well recognized for their multidrug resistance. Acyl-homoserine lactone (Acyl-HSL) based Quorum sensing (QS) is known to regulate virulence and biofilm maturation in these organisms; hence, inhibition of QS will help to control their pathogenicity. In the study, 5 plants, Rubia cordifolia, Tinospora cordifolia, ...

Ayurveda is one of the oldest systems medicine in world. There are almost 1200 plants mentioned for their medicinal properties. Thus, Pharma therapeutics mainly centered on use various plant parts management innumerable diseases. Guduchi (Tinospora cordifolia (Willd.) Hook. F. & Thoms.) Is such praise widely its efficacy treatment diseases along with superior rejuvenation property? Ayurvedic ph...

The present study investigated the antiarrhythmic activity of alcoholic extract of Tinospora cordifolia (T. cordifolia) in CaCl2 induced arrhythmia. CaCl2 (25 mg/kg) was administered by intravenous infusion (iv) to produce arrhythmia in rats. The animals were then treated with T. cordifolia extract (150, 250, and 450 mg/kg) and verapamil (5 mg/kg,iv). Lead II electrocardiogram was monitored. Pl...

INTRODUCTION Pain is a very well-known signal of ill health and analgesics are the drugs that are used to relieve pain. The main problem with these drugs remains that of side effects. Safer alternatives are natural herbs. Guduchi (Tinospora cordifolia) is one such plant with analgesic potential but few studies are there. OBJECTIVE To evaluate the analgesic activity of commercially available e...

Phytochemical investigation of the chloroform extract of Tinospora cordifolia yielded a new clerodane diterpenoid tincordin along with tinosporide, 8-hydroxytinosporide, columbin, 8-hydroxycolumbin and 10-hydroxycolumbin. The structure of the new compound was elucidated comprehensively using 1D and 2D NMR methods. All major clerodane diterpenoids isolated were tested for their efficacy as insec...

Objective: The present investigation has been carried out to evaluate the possible radio protective potential of Tinospora cordifolia root extract (TCE) against 2.5 Gy gamma radiations induced biochemical alterations in the liver of Swiss albino mice. Methods: For this purpose, healthy Swiss albino male mice were selected from an inbred colony and divided into four groups. Group I (normal) was ...

Argwadhadhi Kwatham is a compound preparation of 3 single drugs viz cassia fistula L. Azadirachta indica A., Tinospora cordifolia L. Literature survey show tat all3 ingredients are very effective for skin diseases. Kahayams prepared individually with these 3 drugs was found to be more effective for skin dideases. This paper deals with a comparative study of the chemical constituents present in ...

Background: Heat stress in animals can occur when ambient temperatures are high and wind speeds low, resulting diminished growth, poor health, or even death. The purpose of this study is to evaluate the effect Tinospora cordifolia (TC) on anti-stress blood biochemical parameters heat stressed (HS) Gaddi goats. Methods: Sixteen adult male goats were split into four groups, T0H0 (no supplement no...