OBJECTIVE To investigate the association between pernicious anemia and other autoimmune diseases. METHODS This retrospective and bicentric study was conducted at Reims and Strasbourg University Hospitals and involved 188 patients with pernicious anemia examined between 2000 and 2010 in order to search for other autoimmune diseases and to evaluate the role of pernicious anemia in autoimmune po...

Our patient developed Riedel's thyroiditis soon after having an exacerbation of multiple sclerosis (MS). MS has been associated with other autoimmune diseases, including thyroiditis, and both Hashimoto's thyroiditis and subacute thyroiditis have been described in connection with MS. Yet, we are not aware of any other patient reported to have concomitant MS and Riedel's thyroiditis. The associat...

BACKGROUND Common autoimmune disorders tend to coexist in the same subjects and to cluster in families. METHODS We performed a cross-sectional multicenter study of 3286 Caucasian subjects (2791 with Graves' disease; 495 with Hashimoto's thyroiditis) attending UK hospital thyroid clinics to quantify the prevalence of coexisting autoimmune disorders. All subjects completed a structured question...

Hashimoto's thyroiditis, a common autoimmune disease, is associated with autoantibodies to thyroglobulin (Tg) and thyroid peroxidase (TPO). TPO, unlike abundant and easily purified Tg, is rarely investigated as an autoantigen in animals. We asked whether antibodies (Abs) develop to both TPO and Tg in thyroiditis that is induced (C57BL/6 and DBA/1 mice) or arises spontaneously (NOD.H-2h4 mice). ...

A 25 year old female presented with hypothyroidism which was followed by the development of hyperthyroidism about 1 1/2 years later. This uncommon phenomenon is postulated to result from changes in the relative amounts of stimulatory and inhibitory TSH receptor antibodies. This case illustrates the possible continuum between Graves' disease and Hashimoto's thyroiditis within the broad spectrum ...

Objective — to study the effects of cholecalciferol on level anxiety in patients with autoimmune thyroiditis and hypothyroidism Western Ukrainian population.
 Materials methods. The included 56 caused by thyroiditis. Hypothyroidism was diagnosed under guidance recommendations American Association Clinical Endocrinologists 2012. To verify thyroiditis, following taken into account: related c...

The most common cause of acquired thyroid dysfunction is autoimmune disease (AITD), which commonly manifests as Hashimoto's thyroiditis (HT) or Graves' (GD). importance vitamin D (vit D) an immune modulator has recently been emphasized in several types disorders. However, its significance illnesses not fully understood. purpose this study to investigate how affects the pathophysiology hyperthyr...

: Chronic lymphocytic thyroiditis is autoimmune thyroiditis; it considered as second most common thyroid disorder diagnosed on FNAC following colloid goitre. a reliable and efficient method for diagnosing these lesions. Lymphocytic frequently affects women, primarily compared to men commonly found with hypothyroidism, euthyroidism or every so often hyperthyroidism. The incidence rate of Hashimo...

Pemphigus foliaceus (PF) is an autoimmune blistering disease presenting in endemic and sporadic forms. The typical presentation is recurrent shallow erosions in a seborrheic distribution. PF has also been found in association with autoimmune diseases such as autoimmune thyroid disease (e.g. toxic nodular goiter and Hashimoto’s thyroiditis). In some patients, PF appears to be triggered by radioi...

To study the role of invariant Natural Killer T cell ( iNKT) cells in autoimmune thyroiditis, we derived two iNKT cell lines from the spleens of NOD· H2(h4) mice, a strain that develops spontaneous autoimmune thyroiditis exacerbated by excess dietary iodine. The two lines were CD1d-restricted and expressed CD4(+), DX5(+), and the Vα4Jα281 gene segment, of the T-cell receptor α locus. Upon stimu...