A 34-year-old woman presented with a 2-year history of anterior midline neck swelling. The physical examination revealed a soft, mobile, nontender, 2 × 1 cm, anterior midline neck mass. Ultrasonography showed a heterogeneously isoechoic mass (2.23 × 1.18 cm) in the subhyoid region, while a thyroid gland was not seen in the normal position (Fig. 1A). A 99mTc-pertechnetate scan demonstrated two d...

What is TSH? TSH is produced and secreted by basophilic cells called “thyrotrophs” in the anterior pituitary gland of vertebrates from fishes to mammals. TSH is also called thyrotropic hormone or thyrotropin. TSH acts on thyroid gland, adipose tissue, eye, and so on. TSH receptor penetrates the cell membrane 7 times and is coupled with G-protein-PKA system. TSH increases the release of thyroid ...

background: considering the controversial information regarding the effects of perchlorate on thyroid function of high risk population as neonates, and given the high prevalence rate of thyroid disorders specially congenital hypothyroidism in our region, this study aims to investigate for the frst time in iran, the relationship between drinking groundwater perchlorate and cord blood thyroid hor...

ectopic thyroid tissue (ett) is a rare entity and a challenging differential diagnosis. this is a report of a case of a mediastinal mass that was found to be an ectopic mediastinal thyroid tissue, in a 77-year-old woman who was admitted to our hospital for breast cancer management. the mediastinal mass was identified in the postsurgical computed tomography (ct) scan of the chest and was suspect...

It is the present acceptance in general that the level of dietary iodine is of paramount importance for the proper working of the thyroid gland. Remington low iodine diet is much used for studies on iodine deficiency in rats. This diet induces the hyperactive state of the thyroid gland, which is proved by the increase of I131 uptake and thyroid/serum radioiodide concentration ratio(T/S ratio)or...

An ectopic thyroid is a form of thyroid dysgenesis in which an entire or parts of the thyroid gland may be located in another part of the body than what is the usual place. The most frequent location is the base of tongue. Although most cases are asymptomatic, symptoms related to tumor size and its relationship with surrounding tissues, hormonal dysfunction and seldom malignancy may also occur....

F-18 FDG is the most widely used tracer in molecular imaging and it is applied for many purposes mainly in malignant diseases. Incidental finding are common in FDG-PET/CT imaging and includes benign and malignant lesions. Among the rare tumors , adrenal oncocytomas are uncommon findings and incidental findings of thyroid malignancies are not rare. Oncocytoma is a rare adrenocortical tumor and m...

OBJECTIVE The purpose of the current study is to examine the incidence and clinical significance of unexpected focal uptake of 18F-fluorodeoxyglucose (18F-FDG) on positron emission tomography/computed tomography (PET/CT) in the thyroid gland of oncology patients, the maximum standardized uptake value (SUVmax) of benign and malignant thyroid incidentalomas in these patients, and review the liter...

Thyroid associated ophthalmopathy is a constellation of symptoms caused by an autoimmune process involving the orbital tissue. It is common in hyperthyroid patients due to Graves' disease and also reported in euthyroid and hypothyroid Graves' patients with positive thyroid receptor antibodies. But in Hashimoto's thyroiditis, thyroid associated ophthalmopathy is a rarely reported and poorly unde...

We herein describe a case of Marine-Lenhart syndrome with a negative TSH receptor antibody titer. A 75-year-old female presented to our hospital with malaise, palpitations, and mild fine tremors. She did not have any signs suggestive of Graves' ophthalmopathy, including conjunctival injection, periorbital edema, or proptosis. Her laboratory data were negative for thyroid autoantibodies, includi...