1. What are the signs and symptoms of hyperthyroidism? General: Heat intolerance, perspiration, flushing, tremor, sleep disturbance, or hair loss. Psychological: Nervousness, emotional lability, anxiety, aggressiveness, or delusions. Cardiovascular: Palpitations, tachycardia, or supraventricular dysrhythmias. Respiratory: Breathlessness or hoarseness. Gastrointestinal: Increased appetite, weigh...

There is growing recognition of the association between the use of gadolinium-containing radiocontrast agents for magnetic resonance imaging and the serious dermal and systemic disease nephrogenic fibrosing dermopathy/nephrogenic systemic fibrosis (NFD/NSF). The pathogenesis of this entity remains unclear; however, our recent observations suggest a likely mechanism for the initial dermal manife...

Restrictive dermopathy is a lethal autosomal recessive skin disease. Prenatal diagnosis has not yet been reported. We present a case of restrictive demography and describe the associated prenatal sonographic findings. A continuously open mouth was the most striking feature and this sonographic finding may be a marker of a skin disease.

Nephrogenic systemic fibrosis, initially called nephrogenic fibrosing dermopathy, has been strongly linked to exposure to gadolinium-based contrast media used in magnetic resonance imaging in patients with renal insufficiency. This review discusses recent advances in our understanding of the pathophysiology and clinical approach to patients with chronic kidney disease who require diagnostic ima...