نتایج جستجو برای: thrombocythemia
تعداد نتایج: 1972 فیلتر نتایج به سال:
Essential thrombocythemia is very rare during childhood. The pseudo-electrolyte imbalances including hyperkalemia and hypercalcemia have been reported among adult patients with this condition. Due to the rarity of this condition in the pediatric age group, overtreatment and even hospitalization of these patients for correction of electrolyte imbalances is usually inevitable. Herein, we reviewed...
grelide in young patients with essential thrombocythemia. Blood 2001;97:863-6. 12 Harrison CN, Campbell PJ, Buck G, Wheatley K et al. A randomised comparison of hydroxyurea and anagrelide in highrisk essential thrombocythemia: the Medical Research Countil PT-1 Trial. N Engl J Med (in press). 13 Tefferi A. Myelofibrosis with myeloid metaplasia. Review. N Engl J Med 2000;342: 1255–65. 14 Tefferi ...
Erythromelalgia is a rare neurovascular pain syndrome characterized by a triad of redness, increased temperature, and burning pain primarily in the extremities. Erythromelalgia can present as a primary or secondary form, and secondary erythromelalgia associated with a myeloproliferative disease such as essential thrombocythemia often responds dramatically to aspirin therapy, as in the present c...
A patient with primary thrombocythemia, who was heterozygous for glucose-6-phosphate dehydrogenase deficiency (GdB/GdMed), was investigated to test for the clonal origin of this myeloproliferative disorder. In order to assess somatic cell mosaicism in various tissues, we have made use of the different rate of utilization of 2-deoxyglucose-6-phosphate, an analog of glucose-6-phosphate, by normal...
Essential thrombocytherrlia, considered one of the least common of the myeloproliferative disorders, is being diag nosed more frequently with the increasing use of automated blood cell counters. Essential thrombocythemia described by Epstein and Goendel in 1934 is a diagnosis of exclusion i.e., exclusion of all sy stemic conditions associated with thrombocytosis in an individual with a persiste...
BACKGROUND AND OBJECTIVES Although anagrelide is widely used in the treatment of thrombocythemia in myeloproliferative diseases, there is currently limited information on the efficacy and toxicity of its long-term use. This prospective study investigated clinical toxicity and efficacy of anagrelide during two years of treatment. DESIGN AND METHODS A multicenter, open, phase II study of anagre...
BACKGROUND Refractory anemia with ring sideroblasts associated with marked thrombocytosis was proposed as a provisional entity in the 2001 World Health Organization classification of myeloid neoplasms and also in the 2008 version, but its existence as a single entity is contested. We wish to define the clinical features of this rare myelodysplastic/myeloproliferative neoplasm and to compare its...
The clinical course of polycythemia vera and essential thrombocythemia is potentially associated with long-term severe complications, such as evolution to myelofibrosis or acute myeloid leukemia. Allogeneic stem cell transplantation is currently the only potentially curative treatment for advanced polycythemia vera or essential thrombocythemia. We analyzed 250 consecutive patients with an initi...
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