DNA methyltransferase-1 (DNMT1) has a higher specific activity on hemimethylated DNA than on unmethylated DNA, but this preference is too small to explain the faithful mitotic inheritance of genomic methylation patterns. New genetic studies in plants and mammals have identified a novel factor that increases the fidelity of maintenance methylation.

The aim of this contribution is to present some unknown features of the already well-known Physiotherapy Evidence Database (PEDro) with some useful skills to make your search more effective.