OBJECTIVE Reduced lopinavir concentrations have been demonstrated with use of the capsule formulation during the third trimester of pregnancy. This study determined lopinavir exposure with an increased dose of the new tablet formulation during the third trimester. DESIGN International Maternal Pediatric Adolescent AIDS Clinical Trials 1026s is a prospective nonblinded pharmacokinetic study in...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background : this study aimed to investigate the associations between macro- and micronutrients received in the first, second, and third trimesters and risk for preeclampsia considering demographic and reproductive characteristics and physical activity. methods : in this prospective cohort study, data was collected by fill...

Cushing's syndrome (CS) during pregnancy is a rare condition with significant maternal and fetal complications. A case of CS during the third trimester of pregnancy secondary to adrenocortical adenoma was reported. Literature review revealed the disadvantages of different treatments in this period. Besides the conservative treatment, surgery is recommended for CS during the third trimester of p...

Primary hyperparathyroidism (PHPT) is rare condition during pregnancy; however, it can carry significant risks to both mother and foetus during and after the pregnancy. The definitive treatment is parathyroidectomy undertaken preferably in the second or early third trimester. A case of asymptomatic PHPT diagnosed and treated by parathyroidectomy in the third trimester is described.

background: childbearing years in the women's life are associated with the highest risk of depression. in this study depression in third trimester of pregnancy and after delivery was studied. depressive symptom score and the proportion of mothers above a threshold were compared to indicate probable depressive disorder at each stage. methods : this prospective cohort study was conducted in rural...

INTRODUCTION Protein S (PS) activity has been shown to decrease during normal pregnancy. The aim of this study was to determine any correlation between decreased maternal PS activity and fetal growth restriction (FGR). METHODS We carried out a retrospective study of maternal PS activity and complement 4b-binding protein (C4BP) concentration in 102 patients with FGR and 58 patients with fetuse...

OBJECTIVE The purpose of this study was to assess the contribution of obesity on quality of a woman's life during pregnancy. STUDY DESIGN At the Hospital of Gynecology and Obstetrics in León, Mexico, we followed-up 220 pregnant women (110 obese and 110 nonobese) who completed the 12-item short-form health survey at the beginning and during the third trimester of pregnancy. RESULTS The menta...