The role of Cu and Zn ions in Alzheimer's disease is linked to the consequences of their coordination to the amyloid-β (Aβ) peptide, i.e. to the modulation of Aβ aggregation and to the production of Reactive Oxygen Species (ROS), two central events of the so-called amyloid cascade. The role of both ions in Aβ aggregation is still controversial. Conversely the higher toxicity of the redox compet...

abortion traditionally means miscarriage and is still known as a problem, which societies have been trying to reduce its rate by using legal means. despite the fact that  pregnant women and fetuses have been historically supported;  abortion  was firstly criminalized in 1926 in iran, 20 years after establishment of modern legal system. during next 53 years this situation changed dramatically, t...

background uterine artery embolization (uae) is a minimally invasive procedure performed under fluoroscopy for the treatment of uterine fibroids and accompanied by radiation exposure. objectives to compare ovarian radiation doses during uterine artery embolization (uae) in patients using conventional digital subtraction angiography (dsa) with those using digital flat-panel technology. patients ...

The role of Cu and Zn ions in Alzheimer’s disease is linked to the consequences of their coordination to the amyloid-β (Aβ) peptide, i.e. to the modulation of Aβ aggregation and to the production of Reactive Oxygen Species (ROS), two central events of the so-called amyloid cascade. The role of both ions in Aβ aggregation is still controversial. Conversely the higher toxicity of the redox compet...

background: heavy metals, even at low concentrations, are harmful to human health and environment. cadmium as a heavy metal is highly toxic and can cause serious threat to living organisms. this research was designed to evaluate the adsorption potential of modified magnetic iron nanoparticles by 2-(5-bromo-2-pyridylazo)-5-diethylaminophenol ligand for the removal of cadmium ions from water solu...

background: the present study investigated the effect of the middle east dust storm episodes on the concentration and composition of pm 10 during april to september 2013 in sanandaj city, western iran. methods: sampling was once every six days, and on dusty days using an omni air sampler. the pm 10 sample was collected on polytetrafluoroethylene filters. average of 24 h values of pm 10 mass con...

spinal cord injury (sci) leads to a significant health problem associated with a broad range of secondary complications and disabilities. in this regard, animal models can help us to understand the pathobiology of sci and evaluate the effects of potential treatments for sci. in contusion models of sci, different devices including surgical spring-loaded clips, balloons, forceps, weights and the ...

background: mushroom tyrosinase a potent candidate in clinical studies known as polyphenol oxidase, is a metaloenzyme from the oxidase superfamily widely distributed from lower to higher life forms. it plays a crucial role in sclerotization of exoskeleton in insects, also responsible for skin pigmentation in mammalians. objective: in this study, after reconstitution of mt by some metal ions, th...