BACKGROUND We examined independent influences of contextual variables on cardiovascular risk factors in Shilin county, Yunnan province, South-west China. METHODS Three villages were selected from each of the ten townships based on probability proportional to size. In each selected village, 200 individuals aged > or = 45 years were chosen based on simple random sampling method. From 6006 indiv...

AIMS To evaluate whether fasting plasma glucose values measured early during insulin therapy can identify patients with Type 2 diabetes who may not achieve adequate glycaemic control after 6 months and will require additional treatment. METHODS Patient-level data from seven prospective, randomized, controlled studies using treat-to-target methods were pooled to evaluate the efficacy of insuli...

The application of various modifications of fasting for its therapeutic value has been well documented during many different periods of our civilization. In the earliest eras of recorded civilization, humans found in fasting not only a method of treatment and prevention of some diseases, but a potent weapon for self-discipline and moral education. For this reason the fast became an integral par...

cardiovascular diseases are the most common causes of human morbidity and mortality despite significant therapeutic improvements by surgical or pharmacological approaches in the last decade. micrornas (mirnas) have a significant role in diseases development or response to treatment. in this review, we summarized the role of mirnas in the pathogenesis or the treatment of coronary artery disease ...

CONTEXT Patients treated with levothyroxine typically ingest it in a fasting state to prevent food impairing its absorption. The serum thyrotropin concentration is the therapeutic index of levothyroxine action. OBJECTIVE The study objective was to determine the effect of the timing of levothyroxine administration in relationship to food on serum thyrotropin levels. DESIGN Participants were ...

BACKGROUND Gastric bypass surgery seems to have an effect on glucose metabolism beyond what is mediated through weight reduction. The magnitude of this effect on fasting and post-challenge glucose levels remains unknown. RESULTS Morbidly obese subjects without known diabetes performed a 75 g oral glucose tolerance test before and after either gastric bypass surgery (n = 64) or an intensive li...

posed to have tlie right to exercise his discretion as regards fasting for a certain number of days, but it is no less than gross cruelty to experimentalise with dogs to ascertain how long they can live without sustenance. Such experiments, however, have been lately carried out in Paris, where Dr. Laborde laid a report before the Paris Zoological Society on the results of two cases carried on u...

This brief review is aimed to point out the importance of considering glycated hemoglobin, fasting blood glucose, post-glucose-load glycemia, and postprandial glycemia into an evolutive and dynamic criteria that may grant a better concept and understanding of the diagnostic and therapeutic status of individual patients with type-2 diabetes mellitus.

AIM To identify biochemical and genetic variation relating to increased risk of developing type 2 diabetes mellitus and cardiovascular disease in young, lean male and female adults of different ethnicities. METHOD Fasting blood and urine and non-fasting blood following oral glucose intake were analysed in 90 Caucasians, South Asians and South East/East Asians. RESULTS There were no differen...