نتایج جستجو برای: therapeutic and diagnostic proteins
تعداد نتایج: 16939518 فیلتر نتایج به سال:
prohibitins are chaperone proteins highly conserved among eukaryotes. many different functions have been attributed to prohibitins depending on their tissue expression and sub-cellular localization. prohibitins play a major role in mitochondrial physiology, regulating the stability and the processing of both respiratory chain complex subunits and opa1, a mitochondrial fusion regulating protein....
background : the aim of this study was to generate in silico 3d-structure of the envelope protein of ahfv using homology modeling method to further predict its conformational epitopes and help other studies to investigate its structural features using the model. methods : a 3d-structure prediction was developed for the envelope protein of alkhumra haemorrhagic fever virus (ahfv), an emerging ti...
It is degraded to free triglycerides and fatty acids by the secreted phosphatases of plant family (sPLA2s). Plants have very few sPLA2s. Plant sPLA2s' molecular, biochemical, catalytic properties are being studied. Three-dimensional structures also included when comparing two groups. Glycine max used as a benchmark for various organisms, including any herbal plants small animals. In addition, t...
This review aimed to present Chlamydomonas reinhardtii as an alternative for heterologous protein production, especially biopharmaceuticals, and its general characteristics when compared with other expression systems. The need produce proteins industrial interest, therapeutic ends, diagnostic kits has led the development of recombinant microalgal technology. technology presents some interesting...
Lung cancer is one of the most prevalent cancers and has very poor treatment outcome. Biomarkers useful for screening and assessing early therapeutic response may significantly improve the therapeutic outcome but are still lacking. In this study, serum samples from 218 non-small cell lung cancer (NSCLC) patients, 34 small cell lung cancer (SCLC) patients and 171 matched healthy controls from Ch...
Background: Increase of protein purity is a serious challenge in the production of recombinant therapeutic proteins. For this purpose, several strategies have been employed to purify the target protein, among which the affinity chromatography-based purification methods and tagged proteins such as Ni-NTA are common and but costly. Therefore column-free purification techniques, such as using elas...
abstract amino acids are building blocks of proteins, and play a vital role in living beings existence and their functionality. the interaction of these compounds with metal ions is of great importance to biochemists, and chemists, because their functions can be utilized as a model in understanding enzymes mechanism for transport of metal ions to tissues. among twenty essential amino acids w...
background: lipopolysaccharides (lpss) and several antigenic proteins of brucella have been considered for preparation of diagnostic reagents and subunit vaccines. the objective of this study was to identify and compare immunogens of b. abortus s19 which induce humoral immune responses in human, goat and rabbit. material and methods: the bacterial whole cell extract was prepared in extraction...
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