The structures of atpenins A4, A5 and B, new antifungal antibiotics produced by Penicillium sp., have been deduced to be I, II and III, respectively, on the basis of spectroscopic and 1H and 13C NMR spectral data. The molecular structure of atpenin A4 with absolute configurations was finally confirmed to be 2'S,4'S,5'S-5,6-dimethoxy-4-hydroxy-5'-chloro-2',4'- dimethyl-1'-oxoheptyl-2-hydroxypyri...

background and objective: candidiasis is a common opportunistic infection in hiv-infected patients. the spectrum of candida infection is diverse, starting from asymptomatic colonization to pathogenicforms. the low absolute cd4+ t-lymphocyte count has traditionally been cited as the greatest risk factor for the development of oropharyngeal candidiasis and current guidelines suggest increased ris...

Endophytic actinomycetes were isolated from surface sterilized leaves of Catharanthes roseus (L.) G. Don offamily Apocynaceae. A total of 38 endophytic actinomycetes were recovered on Starch Casein Agar.Among the 38 isolates 20 morphologically different isolates were screened for antibacterial activity againstBacillus subtilis, Staphylococcus aureus, Pseudomonas aeruginosa, Pr...

trichoderma species are among important antagonists of plant pathogenic fungi. the main purpose of this study was to evaluate the biocontrol potential of native trichoderma spp. isolates from sugar beet fields against phytophthora drechsleri and p. cryptogea, the causal agents of phytophthora root rot of sugar beet. during 2007–08, 85 isolates of trichoderma spp. from sugar beet fields in eight...

background and purpose :candidiasis is a widespread fungal infection caused by different candida species. rapid identification of candida species in clinical laboratory is becoming increasingly important since the identification and discrimination of ethological agents for early treatment. we aimed at molecular identification of commonly candida species isolated from clinical samples by using b...

conclusions in this study, snpcr was specific and more sensitive than the chromogenic medium chromagar™ candida for the detection of candida spp. insofar as it failed to identify only a few isolates. materials and methods we used snpcr with universal and species-specific primers to detect candida species in the culture of clinical isolates. by using universal primers, we carried out the amplifi...

Although more than 3000 antibiotics have been reported from Actinomycetes/ higher fungi; biotechnological potential of yeasts and yeast-like fungi with respect to production of antimicrobial compounds has not been sufficiently investigated. We examined the antimicrobial activity of 11 strains of Aureobasidium pullulans (two new isolates and nine standard strains). All the strains of Aureobasidi...

Although more than 3000 antibiotics have been reported from Actinomycetes/ higher fungi; biotechnological potential of yeasts and yeast-like fungi with respect to production of antimicrobial compounds has not been sufficiently investigated. We examined the antimicrobial activity of 11 strains of Aureobasidium pullulans (two new isolates and nine standard strains). All the strains of Aureobasidi...