After a 4-minute i.v. dipyridamole infusion, 0.14 mg/kg/min, serial thallium-201 scans were obtained in 60 patients undergoing cardiac catheterization. Forty patients had significant (> 50% stenosis) coronary artery disease (CAD), and 20 patients had normal coronary arteries or trivial lesions. The images were graded qualitatively for thallium activity by three observers. Sensitivity was 93% (3...

Myocardial perfusion scintigraphy is an established method in cardiology for the diagnosis and evaluation of coronary artery disease (CAD). Thallium-201 and Tc-99m sestamibi myocardial perfusion imaging has been widely accepted as non-invasive diagnostic procedure for detection of CAD, risk stratification and myocardial viability assessment. But, standard Tl-201 redistribution and same day or 2...

The sensitivity of myocardial perfusion imaging (MPI) using thallium-201 injected both at rest and during peak exercise was compared to simultaneously recorded 12 lead electrocardiography (ECG) for the detection of transient ischemia in 20 normal subjects and 63 patients with coronary artery disease (CAD). No significant perfusion defects or ECG changes were seen on either the rest or exercise ...

Fifty patients with acute chest pain had thallium-201 myocardial imaging performed three to six days after emergency admission to hospital. The image was abnormal in 20 out of 22 patients with acute transmural myocardial infarcts but in only 1 of 5 with acute subendocardial infarcts. Indistinguishable scan abnormalities caused by old infarcts were seen in 7 patients, and caused by myocardial is...

This study was undertaken to examine the ability of SPECT in differentiation of a pulmonary lesion suspecions of lung cancr. A total of 170 patients with suspected lung cancer were studied. A dose of Tl-201 chloride {148-296 MBq) was injected intravenously and tomographic early and delayed scans were obtained at 15 miniutes and 3 hours post injection, respectively. Delayed Tl-201 SPECT vi...

vessel coronary artery disease. Circulation. 57 (suppl I): 1-50, 1978 31. Brownlee KA: Statistical Theory and Methodology in Science and Engineering. New York, John Wiley and Sons, 1967, p 349 32. Cook DJ, Bailey I, Strauss HW, Rouleau J, Wagner HN Jr, Pitt B: Thallium-201 for myocardial imaging: appearance of the normal heart. J Nucl Med 17: 583, 1976 33. Bradfield JWB, Beck G, Vecht RJ: Left ...

To determine whether the severity of thallium-201 scintigraphic defects present within hours of acute myocardial infarction (MI) could he used to predict subsequent mortality, thallium-201 imaging was performed within 15 hours of the onset of symptoms in 42 patients with acute MI. Patients with pulmonary edema or shock were excluded. The extent of perfusion defect was determined in three views ...