background and aims: cytomegalovirus (cmv) has worldwide distribution, and its prevalence rate depends on factors such as economic and geographical conditions. an important way of the virus transmission is via blood. due to high prevalence of anti-cmv antibodies in blood donors and lack of data concerning its seroprevalence in the region, this study was carried out to determine the prevalence r...

background: coeliac disease is triggered by ingestion of gluten-containing cereals in genetically susceptible subjects. the aim of the study was to analyze correlation between serum antiendomysial antibody and antiglidin antibody and the grade of pathology in small intestine mucosa in children with celiac disease. materials and methods: this cross-sectional analysis was carried out in a group o...

background: the autoimmune disease known as idiopathic (immune thrombocytopenic purpura thrombocytopenic purpura (itp) is clinically defined by a low numbers of platelets in the circulation blood. this study aimed to isolate autoantibodies made against the platelet glycoproteins using platelets from healthy volunteers, to determine their specificity and further elucidate their effects on platel...

background: thalassemia patients are more susceptible to hepatitis than the normal population due to the frequent blood transfusions. objective: to determine the immune response of children with major ß-thalassemia, by measuring anti-hepatitis b surface antibody (anti-hbs ab) following the last hbv vaccine injection. methods: this study was carried out on 215 thalassemic children who received t...

abstract background thalassemia patients that are conventionally treated by a regular transfusion regimen are exposed to blood born viral infections.the aim of this study was to investigate the seroprevalence of hepatitis b virus (hbv), hepatitis c virus (hcv) , and human immunodeficiency virus(hiv) among all multitransfused thalassemia patients in west north of iran. material and methods a ret...

background: human cd34 is a transmembrane glycoprotein which is expressed in human hematopoietic stem cells (hscs) and the small- vessel endothelial cells of a variety of tissues. cd34 plays a critical role as a marker for diagnosis and classification of leukemia. anti cd34 antibodies are used for isolation and purification of hscs from bone marrow, peripheral blood and cord blood. objective: t...

Background: Anti-thyroid peroxidase antibody (anti-TPO antibody) is a member of thyroid autoantibodies which are important in inducing and also diagnosing autoimmune thyroid diseases. Thyroid autoimmunity can cause several forms of thyroiditis and abnormal thyroid functions, ranging from hypothyroidism to hyperthyroidism. Objective: To evaluate the relationship between serum levels of anti-TPO ...

chlamydia trachomatis is an obligate intracellular bacterium which causes a wide variety of human infections such as ocular, urogenital and respiratory infections. genital infections of women, espe-cially when repeated, give rise to many complications such as ectopic pregnancy, miscarriage and in fertility. since chlamydial infections are usually asymptomatic, they progress unnoticed and produc...