B-type synthetic carbonate hydroxyapatite (CHAp), natural carbonate fluorapatite (CFAp) and silicon-substituted hydroxyapatite (SiHAp) have been studied by using micro-Raman and infrared (IR) spectroscopy. It was found that while B-type carbonate substitution predominates in carbonate apatites (CAps), A-type is also detected. B-type carbonate substitution causes a broadening of the v(1) P-O str...

India Human Development Survey was funded by grants R01HD041455 and R01HD061048 from the US National Institutes of Health and a supplementary grant from the Ford Foundation. Data analysis was funded by the UK government as part of its Knowledge Partnership Programme. We gratefully acknowledge inputs from Reeve Vanneman and Amaresh Dubey and participants in a roundtable on “Caring for the Elderl...

Some aryl and heteroaryl azido compounds were synthesized from the reaction of corresponding fluoro and chloro compounds with sodium azide in DMF as solvent and under various reaction conditions especially ultrasonic irradiation. Reaction of aromatic and heteroaromatic azido compound with thioacetic acid in the presence of sodium hydrogen carbonate and in methanol as solvent led to the differen...

Reaction of dialkyl acetylenedicarboxylates 1a-c andpyrrole derivatives 2a-e in the presence of triphenylphosphite (TPP) was investigated and the effect of the pyrrole substitution was established. Diastereoselectivity is observed with pyrroles, 2a,b, yieldingphosphonate ester derivatives 3a-f and 4,and their relative configuration is determined by 1H/13C and 31</...

Antimitotic natural products that bind to cellular microtubules can be used as anticancer agents, and we are studying the cellular mechanisms of these compounds.1 The fungal metabolite phomopsin A is a key structure in these studies, and we are currently pursuing its synthesis.2 Our retrosynthetic analysis of phomopsin A targeted the chiral tertiary alkyl-aryl ether as a key disconnection withi...