Objectives: This study aimed to evaluate the effect of crocin and treadmill exercise on oxidative stress, sperm parameters, testis structure in streptozotocin (STZ)-induced diabetic rats. Materials Methods: In this experimental study, 64 rats induced by a single intraperitoneal (IP) injection STZ (50 mg/ kg) were assigned following groups (n=8/each): healthy control group, group treated daily w...

ferula asafoetida contains coumarins and sesquiterpens compounds that have been traditionally used to treat diseases such as nervous disorders, asthma, gastrointestinal disease and epilepsy. sulfur-containing compounds of asafoetida act as antioxidants. this study aimed to investigate the effect of four levels of water-alcoholic extract of asafoetida on reproductive performance of male wistar r...

Exposure to arsenic is linked a wide range of diseases, in particular male reproductive toxicities. Trametes versicolor traditional medicinal fungus with remarkable potential for antioxidant activity. The purpose this study was examine the ameliorating effects water and methanol extracts T. on arsenic-induced toxicities via abrogation oxidative stress. mice were divided as follows: control: nor...

Cadmium is a most toxic heavy metal and an environmental pollutant. The present study was conducted to evaluate the antioxidant role of vitamin E in cadmium chloride (Cdcl2) induced testicular toxicity in rats. .Male wistar albino rats (n=6/group) were divided into control group (saline injected), untreated experimental groups (Single dose of 1mg and 2mg/kg BW, intraperitonially), and pretreate...

epidemiological data suggest that arsenic ultimately results in cancer in different parts of the body. several synthetic therapeutic agents manifest inadequate potency with severe side effects against arsenic toxicity. the flesh of b. bengalensis , has long been used as an ethno-medicine in case of arthritis, blood-impurities, impaired immune system, conjunctivitis and liver anomalies. this pot...

Background: Varicoceles are the abnormal tortuosity and dilatation of the veins of the pampiniform plexus that drain the testis. Recently, studies evaluating the role of oxidative stress in male infertility have shown that infertile men with varicocele have elevated levels of sperm and testicular tissue-derived reactive oxygen species (ROS). Therefore current study was designed to evaluate prot...

BACKGROUND In numerous Caudata, the testis is known to differentiate new lobes at adulthood, leading to a multiple testis. The Iberian ribbed newt Pleurodeles waltl has been studied extensively as a model for sex determination and differentiation. However, the evolution of its testis after metamorphosis is poorly documented. METHODS Testes were obtained from Pleurodeles waltl of different age...

Background and Aims: Diabetes mellitus causes testicular damage by increasing oxidative stress and inflammation. In the present study, modulation of oxidative stress by pioglitazone, a synthetic ligand of peroxisome proliferator-activated receptor-γ, was examined in testis of streptozotocin-induced diabetic rats. Materials and Methods: Diabetes was induced by a single dose of streptozot...

The present study was designed to investigate the potential protective effect of Coenzyme Q10 against the testicular toxicity of cadmium in male rabbits. Four groups of animals were used in this study (control, Coenzyme Q10, cadmium chloride-treated (5 mg/kg), cadmium chloride plus Coenzyme Q10 (10 mg/kg) for 30 days). Results showed normal testicular tissue in control and coenzyme Q10 groups. ...