نتایج جستجو برای: temporin
تعداد نتایج: 109 فیلتر نتایج به سال:
Recent hypotheses suggest that immunosuppression, resulting from altered environmental conditions, may contribute to the increased incidence of amphibian disease around the world. Antimicrobial peptides (AMPs) in amphibian skin are an important innate immune defense against fungal, viral and bacterial pathogens. Their release is tightly coupled with release of the stress hormone noradrenaline (...
The alarming raise of multi-drug resistance among human microbial pathogens makes the development novel therapeutics a priority task. In contrast to conventional antibiotics, antimicrobial peptides (AMPs), besides evoking broad spectrum activity against microorganisms, could offer additional benefits, such as ability neutralize toxins, modulate inflammatory response, eradicate bacterial and fun...
BACKGROUND Antimicrobial peptides (AMPs) play important roles in the innate defense mechanism. The broad spectrum of activity of AMPs requires an efficient permeabilization of the bacterial outer and inner membranes. The outer leaflet of the outer membrane of Gram negative bacteria is made of a specialized lipid called lipopolysaccharide (LPS). The LPS layer is an efficient permeability barrier...
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