ELECTION of a genotype which gives rise to similar phenotypes in different environments is one evolutionary strategy which may result in high adaptedness of a population to the environments in which it lives. Presumably, the stability of certain traits is the outcome of a long history of natural selection tending towards an adaptive phenotype. Several investigators have attempted to select stra...

background: responsiveness is one of the three main goals of the health system introduced by world health organization. this study aimed at examining health system responsiveness after health sector evolution plan in kermanshah, western iran. methods: a sample of 335 hospitalized patients was selected using proportionate allocation to population size method in the city of kermanshah (iran) in 2...

Plant development is highly responsive to ambient temperature, and this trait has been linked to the ability of plants to adapt to climate change. The mechanisms by which natural populations modulate their thermoresponsiveness are not known. To address this, we surveyed Arabidopsis accessions for variation in thermal responsiveness of elongation growth and mapped the corresponding loci. We find...

The role of nitric oxide (NO) in the mediation of cerebrovascular CO2 responsiveness was studied in 10 distinct brain and spinal cord regions of the anesthetized, ventilated, temperature-controlled, normoxic cat. Regional CBF was measured with 15-micron radiolabeled microspheres in hypocapnic, normocapnic, and hypercapnic conditions. CO2 responsiveness of each region was determined from the equ...

ATP-gated P2X3 receptors are expressed by nociceptive neurons and participate in transduction of pain. Responsiveness of P2X3 receptors is strongly reduced at low temperatures, suggesting a role for these receptors in analgesic effects of cooling. Since sustained responsiveness depends on receptor trafficking to the plasma membrane, we employed total internal reflection fluorescence (TIRF) micr...

In the context of global change, the physiological and hormonal stress responses have received much attention because of their implications in terms of allostasis. However, most studies have focused on glucocorticoids only as the "common" response to stressors while neglecting other endocrine axes and hormones (e.g. prolactin, thyroid hormones) that play a crucial role in metabolic adjustments....

Abstract Poly(N-isopropylacrylamide) (PNIPAM) hydrogels are one of the most commonly studied thermoresponsive biomaterials. In this work, we investigate ball milling as a method producing PNIPAM nanogels and confirm that temperature responsiveness is maintained in nanogel form based on hydrodynamic diameter zeta potential measurements.

A dispersion-dominated colorimetric approach for the recognition of carbohydrates based on biomolecule-responsive AuNPs is presented. Taking advantage of the unique dual-responsiveness of smart copolymers, the aggregation and dispersion of AuNPs can be modulated by both temperature and different kinds of carbohydrates, giving rise to a novel chromogenic mechanism for the recognition and testing...