objective(s): auraptene (7-geranyloxycoumarin) (aur), from citrus species has shown anti-inflammatory, neuroprotective, and acetylcholinesterase (ache) and beta-secretase inhibitory effects. scopolamine is a nonselective muscarinic receptor antagonist which causes short-term memory impairments and is used for inducing animal model of alzheimer’s disease (ad). this research aimed to investigate ...

A B S T R A C TIntroduction: Craving to methamphetamine is a significant health concern and exposure to methamphetamine cues in laboratory can induce craving. In this study, a task designing procedure for evaluating methamphetamine cue-induced craving in laboratory conditions is examined. Methods: First a series of visual cues which could induce craving was identified by 5 discussion sessions b...

We describe the ictal [(18)F]FDG-PET study of a case of absence status showing bilateral thalamic hypermetabolism and frontal cortex hypometabolism. This is the first ictal assessment of absence status by [(18)F]FDG-PET reporting this particular cortical and subcortical involvement. Our findings support the theory of corticothalamic circuitry involvement in the pathophysiology of absence seizur...

Serotonin specific reuptake inhibitors (SSRI) may induce antinociception however, the mechanism of this effect is not clear. SSRls increase 5-HT levels in neuronal synapses and facilitate serotonergic activity. In this study, therefore, the activity of para-chlorophenylalanine (pCPA), which reduces 5-HT release, and 5- hydroxy tryptophan (5-HTP), a precursor of 5-HT, were examined on the a...

hydatid disease is a rare parasitic disease, which mainly involves liver then lung tissues. cardiac involvement is very rare, especially when there is not hepatic involvement. we describe a 47-year-old woman with a history of a lung hydatid cyst who was referred to rajaei heart center, tehran, iran in 2012. her chest computed tomographic scan showed a cardiac mass. echocardiographic examination...

this article reports on the findings of a study that investigated the impact of manipulating task performance conditions on listening task performance by learners of english as a foreign language (efl). the study was designed to explore the effects of changing complexity dimensions on listening task performance and to achieve two aims: to see how listening comprehension task performance was aff...

This study examined the effects of input-oriented and output-oriented tasks with different involvement load indices on Iranian EFL learners' comprehension and production of lexical collocations. To achieve this purpose, a sample of 180 intermediate-level EFL learners (both male and female) participated in the study. The participants were in six experimental groups. Each of the groups was random...

Background: Intrauterine infections (TORCH) lead to the involvement of various organs of the body of the fetus, including the eye. The aim of this study was to determine the frequency and clinical response of eye lesions to specific drugs, in infants with confirmed TORCH induced ocular lesions. Methods: This historical cohort study from 2011 to 2017, had done in Pediatrics and Ophthalmology De...

Initially described as task-induced deactivations during goal-directed paradigms of high attentional load, the unresolved functionality of default mode regions has long been assumed to interfere with task performance. However, recent evidence suggests a potential default mode network involvement in fulfilling cognitive demands. We tested this hypothesis in a finger opposition paradigm with task...

serotonin specific reuptake inhibitors (ssri) may induce antinociception however, the mechanism of this effect is not clear. ssrls increase 5-ht levels in neuronal synapses and facilitate serotonergic activity. in this study, therefore, the activity of para-chlorophenylalanine (pcpa), which reduces 5-ht release, and 5- hydroxy tryptophan (5-htp), a precursor of 5-ht, were examined on the antino...