نتایج جستجو برای: targeted nano contrast agent

تعداد نتایج: 814854  

Journal: :Neuro-oncology 2012
Boguslaw Tomanek Umar Iqbal Barbara Blasiak Abedelnasser Abulrob Homam Albaghdadi John R Matyas Dragana Ponjevic Garnette R Sutherland

A mouse model of glioblastoma multiforme was used to determine the accumulation of a targeted contrast agent in tumor vessels. The contrast agent, consisting of superparamagnetic iron oxide coated with dextran, was functionalized with an anti-insulin-like-growth-factor binding protein 7 (anti-IGFBP7) single domain antibody. The near infrared marker, Cy5.5, was also attached for an in vivo fluor...

Journal: :Tissue engineering. Part C, Methods 2014
Ioannis Papantoniou Maarten Sonnaert Liesbet Geris Frank P Luyten Jan Schrooten Greet Kerckhofs

To successfully implement tissue-engineered (TE) constructs as part of a clinical therapy, it is necessary to develop quality control tools that will ensure accurate and consistent TE construct release specifications. Hence, advanced methods to monitor TE construct properties need to be further developed. In this study, we showed proof of concept for contrast-enhanced nanofocus computed tomogra...

Journal: :nanomedicine journal 0
maryam khalkhali department of physics, university of zanjan, zanjan, iranسازمان اصلی تایید شده: دانشگاه زنجان (zanjan university) somayeh sadighian department of pharmaceutical biomaterials, school of pharmacy, zanjan university of medical sciences, zanjan iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی زنجان (zanjan university of medical sciences) kobra rostamizadeh zanjan pharmaceutical nanotechnology research center, zanjan university of medical sciences, zanjan, iran department of medicinal chemistry, school of pharmacy, zanjan university of medical sciences, zanjan, iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی زنجان (zanjan university of medical sciences) farhad khoeini department of physics, university of zanjan, zanjan, iranسازمان اصلی تایید شده: دانشگاه زنجان (zanjan university) mehran naghibi shahid beheshti university of medical sciences, tehran, iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (shahid beheshti university of medical sciences)

objective(s): the aim of this work was to prepare and characterize magnetic nanoparticles (mnps) as theranostic system to act simultaneously as drug carrier and mri contrast agent. chitosan-coated mnps (cmnps) were prepared and loaded with silymarin. silymarin-loaded cmnps were characterized with various techniques and their potential as mri contrast agent was also evaluated. materials and meth...

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Colorectal Cancer (CRC) is the third most common cancer and the second leading cause of cancer-related death all around the world with an estimated 1.2 million new cases and a half million deaths each year. Although some curing methods such as surgery and chemotherapy are used in the early stage of CRC, targeted therapy is one of the principal modes of cancer treatment that could be a reliable ...

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