OBJECTIVE The main objectives of this study were to qualitatively evaluate the profile of phytochemical constituents present in methanolic extract of Microcos paniculata bark (BME) and fruit (FME), as well as to evaluate their anti-inflammatory, analgesic and antipyretic activities. METHODS Phytochemical constituents of BME and FME were determined by different qualitative tests such as Molisc...

the selected parts of four medicinal plants, achillea millefolium, hibiscus rosasinensis, linum usitatissimum and pluchea lanceolata were extracted in absolute methanol to determine their analgesic activity. analgesic activity was assessed on intact mice by tail flick latency via the tail immersion method. the analgesic activities of these plant extracts were compared with acetylsalicylic acid ...

Treatment of mouse tail skins with hexachlorophene (1.25% w/v) in abso­ lute methanol or 70% isopropanol suppressed Schistosoma mansoni infections by more than 95% even when the application was performed up to three days prior to exposure to cercarial suspensions by tail immersion. Treatment with concen­ trations of 0.313% or higher one day prior to exposure provided at least 98% protection whe...

methanolic extract of whole plant of amaranthus viridis l (meav), was screened for antinociceptive activity using acetic acid induced writhing test, hot plate test and tail immersion test in mice. in a similar way a screening exercise was carried out to determine the antipyretic potential of the extract using yeast induced pyrexia method in rats. administration of the extracts was applied to bo...

s | 35 Conclusions: Our findings provide valuable information for personalized pain treatment after LAC, in which the C allele of the rs2076222 SNP is associated with lower opioid sensitivity and/ or higher pain sensitivity and requires more opioid analgesic after LAC. PT642 The effects of caffeine on acupuncture analgesia Jeong Won Hwang, Shoji Shinohara, Tadashi Watsuji, Katsuki Watanabe Abst...

submitted after deadline Evaluation of anaesthetic activity of some aminoalkanol derivatives Tadeusz Librowski1, Anna M. Waszkielewicz2, Barbara Filipek1, Henryk Marona2 !! " #$% & ' !! " # % Derivatives of aminoalkanols such as KM113 and KM314 are considered anticonvulsant drug candidates, and they exhibit sodium channel blocking effect. Therefore, the aim of the study was to determine possibl...

Although the N-arachidonoyl ethanolamine (anandamide) binds to cannabinoid receptors and has been implicated in the suppression of pain, its rapid catabolism in vivo by fatty acid amide hydrolase (FAAH) has presented a challenge in investigating the physiological functions of this endogenous cannabinoid. In order to test whether anandamide and other non-cannabinoid fatty amides modulate nocicep...

The ethanol and water extracts of Sansevieria trifasciata leaves showed dose-dependent and significant (P < 0.05) increase in pain threshold in tail-immersion test. Moreover, both the extracts (100 - 200 mg/kg) exhibited a dose-dependent inhibition of writhing and also showed a significant (P < 0.001) inhibition of both phases of the formalin pain test. The ethanol extract (200 mg/kg) significa...

Chandrashekar. R* and S.N. Rao * & Dept of Pharmacology, Yenepoya Medical College, Yenepoya University, Derlakatte, Mangalore 575018. ABSTRACT : The aim of the study was to investigate the chronic peripheral analgesic activity of Ethanolic Extract of the leaves of Clerodendrum viscosum (EECV) by acetic acid induced writhing reflex test in mice and chronic central analgesic activity of EECV by t...