PURPOSE To develop an accurate method of fusing computed tomography (CT) with magnetic resonance imaging (MRI) for post-implant dosimetry after prostate seed implant brachytherapy. MATERIAL AND METHODS Prostate cancer patients were scheduled to undergo CT and MRI after brachytherapy. We obtained the three MRI sequences on fat-suppressed T1-weighted imaging (FST1-WI), T2-weighted imaging (T2-W...

Introduction: The area at risk (AAR) of infarction is the hypoperfused myocardial bed during coronary occlusion. The edematous AAR can be delineated in-vivo by T2 MRI and can be used in conjunction with delayed contrast enhancement to calculate myocardial salvage. T1 MRI has been recently used to image the edema associated with acute myocardial infarction. Objectives: We hypothesized that, due ...

BACKGROUND Cardiac complications due to iron overload are the most common cause of death in patients with thalassemia major. The aim of this study was to compare iron chelation effects of deferoxamine, deferasirox, and combination of deferoxamine and deferiprone on cardiac and liver iron load measured by T2* MRI. METHODS In this study, 108 patients with thalassemia major aged over 10 years wh...

Background In MRI, fat signal suppression is mandatory for unambiguous visualization of cardiac anatomy but remains challenging at high field. Fat saturation usually directly precedes the imaging portion of a cardiac MRI sequence. It is often used in conjunction with other magnetization preparation modules, such as T2 Preparation (or T2-Prep), to improve blood/myocardium contrast. We propose a ...

Background Patellofemoral pain is common, and treatment is guided by the presence and grade of chondromalacia. Purpose To evaluate and compare the sensitivity and specificity in detecting and grading chondral abnormalities of the patella between proton density fat suppression (PDFS) and T2 mapping magnetic resonance imaging (MRI). Study Design Cohort study; Level of evidence, 2. Methods A...

MRI has provided important insights into the pathophysiology of multiple sclerosis (MS).1 However, conventional MRI scans furnish only gross estimates of the nature and extent of tissue damage associated with MS,2 and the data correlate poorly with measures of concurrent disability in patients. Recent advances in MRI technology have improved the correlation of MRI findings with clinical status ...

INTRODUCTION Major thalassemia patients need lifelong transfusions. The consequence of these repeated transfusions is iron accumulation in different organs. The main aim of the present study was to investigate the correlation between heart, liver and pancreas hemosiderosis in thalassemic patients from Iran. METHODS This cross-sectional study was conducted on 164 major thalassemia patients at ...

OBJECTIVE To evaluate the clinical application of phased-array surface coil intensity correction in magnetic resonance imaging (MRI) in spinal metastases. METHODS 3 phantoms and 50 patients with a corresponding total number of 80 spinal metastases were included in this study. Fast spin echo T1- and T2- weighted MRI with and without surface coil intensity correction was routinely performed for...

Introduction: High resolution MRI at 7T suggests that T2* contrast may be sensitive to white matter composition and microstructure [1]. Preliminary histological and MRI results show that the T2* heterogeneity in white matter may be in part reflect its myelin content [2]. In this study, the quantitative correlation between T2* relaxation rate (R2*=1/ T2*) and diffusion fractional anisotropy (FA)...

Advanced MRI studies demonstrated several diffuse non-lesional features in multiple sclerosis, including changes detectable in gray matter areas. Standard T2 weighted MRI scans of deep gray matter structures, including the thalamus, caudate, putamen, dentate nuclei often demonstrate hypointensity. T2 hypointensity has been shown to correlate with cognitive, neuropsychiatric and motor dysfunctio...