INTRODUCTION: Cerebrospinal fluid (CSF) is important for the hydrodynamic function of the central nervous system. Although long considered as just a partial volume confounder in functional MRI (fMRI), recently a more active role in fMRI contrast mechanism is being investigated for CSF: namely, redistribution in response to local blood volume changes during activation (1,2). As a consequence, ma...

Let A and B be uniform algebras on first-countable, compact Hausdorff spaces X and Y , respectively. For f ∈ A, the peripheral spectrum of f , denoted by σπ(f) = {λ ∈ σ(f) : |λ| = ‖f‖}, is the set of spectral values of maximum modulus. A map T : A → B is weakly peripherally multiplicative if σπ(T (f)T (g)) ∩ σπ(fg) 6= ∅ for all f, g ∈ A. We show that if T is a surjective, weakly peripherally mu...

Tissue water transverse relaxation times (T2) are highly sensitive to fluid and lipid accumulations in skeletal muscles whereas the related T2* is sensitive to changes in tissue oxygenation in addition to factors affecting T2. Diabetes mellitus (DM) affects muscles of lower extremities progressively by impairing blood flow at the macrovascular and microvascular levels. This study is to investig...

BACKGROUND Advances of nanotechnology have led to the development of nano-materials with both potential diagnostic and therapeutic applications. Among them, Super Paramagnetic Iron Oxide Nanoparticles (SPIONs) have received particular attention. Modified EDC coupling fraction was used to fabricate the SPION-C595 as an MR imaging contrast agent for breast cancer detection in early stages. METH...

Introduction. Nephrogenic systemic fibrosis (NSF) is a debilitating fibrosing disorder that develops in patients with underlying kidney disease, following exposure to gadolinium (Gd)-containing magnetic resonance imaging (MRI) contrast agents. Although initially identified as a skin disease, prominent systemic involvement has become evident as more cases have appeared. Gd has been quantified in...

background: iron chelators are an important part of management of patients with thalassemia. it is prudent to compare efficacy of different iron chelators in treatment of iron overload in these patients who receive regular blood transfusion. we aimed to compare the efficacy and safety of available oral iron chelator; deferasirox (exjade®) with deferasirox (osveral®) in reducing iron overload in...

is called the effective domain of F, and F is said to be locally bounded at a point x e D(T) if there exists a neighborhood U of x such that the set (1.4) T(U) = (J{T(u)\ueU} is a bounded subset of X. It is apparent that, given any two monotone operators Tx and T2 from X to X*, the operator F», + T2 is again monotone, where (1 5) (Ti + T2)(x) = Tx(x) + T2(x) = {*? +x% I xf e Tx(x), xt e T2(x)}....

INTRODUCTION Major thalassemia patients need lifelong transfusions. The consequence of these repeated transfusions is iron accumulation in different organs. The main aim of the present study was to investigate the correlation between heart, liver and pancreas hemosiderosis in thalassemic patients from Iran. METHODS This cross-sectional study was conducted on 164 major thalassemia patients at ...

Results 209 cases were reviewed; mean age 47 and 58% men. 74 (35%) patients were diagnosed with myocarditis based on CMR. The number of patients with 0, 1, 2 and 3 criteria positive was 70 (33%), 65 (31%), 49 (23%) and 25 (12%) respectively. Age, gender, diabetes, hypertension, smoking, CAD, prior CHF and CRI were similar among all groups. There was a trend for higher prevalence of NYHA class I...