Introduction Laboratory testing is essential when assessing a patient with a suspected autoimmune rheumatic disease. The results can confirm the possible diagnosis, evaluate disease severity, its complications, and assist in determining the prognosis as well as monitor future disease activity of patients. Systemic autoimmune rheumatic conditions like Systemic lupus erythematous (SLE) or Rheumat...

Lupus enteritis is a rare presentation of systemic lupus erythematous, clinically manifested by abdominal pain, vomiting, and diarrhoea. Proper diagnosis treatment are essential to avoid complications, including death. Here, the authors report case 52-year-old White female who presented with pain chronic diarrhoea, diagnostic tests compatible enteritis. Such condition an uncommon manifestation ...

In response to renal immune complex accumulation in systemic lupus erythematosus (SLE), monocytes, T lymphocytes, and neutrophils infiltrate the kidney and mediate tissue injury and renal dysfunction. Chemotactic factors induced by immune complexes are responsible for recruiting these inflammatory cells to the kidney. Considerable attention has focused on the role of the chemokine network in re...

BACKGROUND Pilot studies have estimated cancer incidence in patients with systemic lupus erythematous (SLE). However, the results have been inconclusive. To ascertain the correlation between SLE and malignancy more comprehensively and precisely, we conducted a meta-analysis. METHODS PubMed, the Cochrane Library and Embase databases through June 2014, were searched to identify observational st...

Signs and symptoms of gonococcal infection in patients with systemic lupus erythematous (SLE) are overlapping and sometimes difficult to distinguish from the manifestations of SLE itself. We are reporting on a patient with a recent SLE flare who developed disseminated gonococcal infection (DGI) as a result of the nature of SLE and the management of a flare.

Systemic lupus erythematous (SLE) is an autoimmune syndrome primarily affecting young women characterized by inflammation in several organs including kidneys, skin, joints, blood and the nervous system. Abnormal immune cellular and humoral responses play key roles in the development of the disease process. Impaired clearance of apoptotic material is a key factor contributing to activation of se...

C ardiac pathology is common in patients with systemic lupus erythematous (SLE).1-6 The pathological involvement includes pericarditis with or without effusion; myocarditis or cardiomyopathy, sometimes with involvement of the conduction system; and myocardial infarction secondary to coronary arteritis, or, more often, atherosclerosis. Left ventricular hypertrophy and left atrial dilatation ofte...

A 47-year-old lady presented with erythematous plaques over bilateral eyebrows and nose regions for about 10 years. She also had a history of systemic lupus erythematosus, idiopathic thrombocytopaenic purpura, interstitial lung disease and chronic hepatitis B. The diagnosis was confirmed to be basaloid follicular hamartoma by histological examination. The patient was treated with potent topical...

lupus erythematosus (le) is an autoimmune disease. the mortality rate and causes of death are different in various countries. the present study is done to find out the causes of mortality in the systemic lupus erythematosus (sle) patients in lupus unit of rheumatology research center and other wards of shariati hospital. this study was retrospective according to medical records of patients who ...

Background: Systemic lupus erythematous is an autoimmune disease associated with atherosclerotic manifestations or metabolic disturbance due to inflammation. The aim of this study was to determine frequency of metabolic syndrome (MetS) in SLE compared to healthy controls. Methods: In this cross-sectional study, 150 SLE patients and 220 healthy volunteers were enrolled. MetS was diagnosed acc...