BACKGROUND Peculiar erythema known as annular erythema associated with Sjögren's syndrome (AESS) can be differentiated from autoimmune annular erythema and subacute cutaneous lupus erythematosus, both clinically and histologically. However, there are no detailed investigations on immune competent cells infiltration. OBJECTIVE Preferential infiltration of interleukin-17-producing T helper (Th1...

Histiocytic necrotizing lymphadenitis or Kikuchi's disease is a rare, benign condition of unknown etiology, which is usually characterized by cervical lymphadenopathy and fever. This disease is rarely associated with systemic lupus erythematosus. Here we describe, for the first time in Iran, a patient who developed systemic lupus erythematosus about 3 years after the initial diagnosis of Kikuch...

macrophage activating syndrome (mas) is a life-threatening disease seen in autoimmune diseases including lupus erythematosus, rheumatoid arthritis, still's disease, polyarteritis nodosa. it is characterized by fever, pancytopenia, liver failure, coagulopathy, and neurologic symptoms and high serum ferritin. a 27 yr. old female patient was admitted in shahid mostafa khomeini hospital (tehra...

background: antiphospholipid antibody syndrome (aps) can either occur as a primary syndrome or associated with other autoimmune diseases such as systemic lupus erythematosus (sle). anticardiolipin antibody (acl) of igg and/or igm isotype in blood, measured by a standardized elisa is the most acceptable laboratory criteria. aps igg isotype, particularly igg2 subclass is more strongly associated ...

how to cite this article: shiari r, hassase yegane m, farivar s, javadi parvaneh v, mirjavadi sa. neuropsychiatric symptoms as the first manifestation of juvenile systemic lupus erythematosus: a complicated case with klinefelter’s syndrome. iran j child neurol. 2014 winter; 8(1):62-65. abstract systemic lupus erythematosus (sle) is an autoimmune, multisystem disorder with various manifestations...

results our study showed that there were no statistically significant differences in the allele and genotype frequencies of -1661 a/g snp between patients with sle and healthy controls (p > 0.05). conclusions in conclusion, we found no association between snp-1661 a/g of the ctla-4 promoter region and susceptibility to sle in our population. objectives to evaluate the potential influences of co...

conclusions the results of this study show that patients with sle have poorer hrqol in physical components whereas the mental component of qol is relatively similar to healthy individuals. depression and anxiety were not related to clinical manifestations of sle. however, the sf domain of hrqol was the most susceptible component of qol, which was affected by sle clinical variables. the high est...