For any given taxonomic divergence event, one may find in the literature a wide range of time estimates. Many factors contribute to the variation in molecular date estimates for the same evolutionary event. High on the list is the choice of calibration points for converting genetic distances into evolutionary rates and, subsequently, into dates of divergence. In this study, we investigate one c...

Individuals with Parkinson's disease and the aged have a high prevalence of falls. Since an increase in the number of falls is associated with physical and psychological harm, it is prudent that biomechanical metrics be established that will accurately assess an individual's walking balance. In this investigation, we initially used a simple bipedal walking computer model to theoretically establ...

Abstract: Steroidal alkaloid cortistatin is a promising marine natural compound isolated from sponges Corticium simplex. Experimental studies and clinical evidence have shown that its derivatives curative effect in patients with autoimmune disorders, HIV infection several types of cancer. The objective our study was to examine the potential cancer-related therapeutic objectives Cortistatin usin...