Results: A total of 54 patients underwent MDO and of those 21 patients were found who have undergone both MDO and DLB. The incidence of at least 1 SAL was 71.4% in this group. A subgroup of patients less than 24 months had an incidence of SALs that was 78%. Types of SALs encountered include laryngeal edema (57.1%), tracheobronchitis (42.9%), laryngomalacia (33.3%), tracheomalacia (14.3%), bronc...

BACKGROUND Hepatocellular carcinoma (HCC) arising in cirrhosis is frequently multifocal. Whether HCC develops monoclonally or multiclonally is an unresolved question. Of the multiple tumour nodules present in many patients, it has not been established whether the smaller lesions represent intrahepatic metastases or de novo cancers. AIMS To assess the degree of genomic heterogeneity in synchro...

Introduction: Although co-occurring thyroid pathologies are common in patients with primary hyperparathyroidism, synchronous parathyroid and differentiated thyroid carcinoma is a rare situation. Case: A 65-year-old woman presented to our endocrinology clinic for evaluation of hypercalcemia. She had an albumin-corrected serum calcium (Ca) concentration of 12.4 mg/dl (normal, 8.6-10 mg/dl), serum...

BACKGROUND Multifocal osteosarcoma is a rare type of tumor which is always excluded from therapy trials and is therefore rarely investigated for prognosis and treatment. PATIENTS AND METHODS Twelve patients with synchronous multifocal osteosarcoma underwent neoadjuvant chemotherapy and, when feasible, simultaneous resection of involved bones. RESULTS Four patients were unsuitable for resect...

This report presents a rare case with the synchronous occurrence of advanced neuroendocrine carcinoma (NEC) and tubular adenocarcinoma of the rectum. A 52-year-old Japanese male presented with general fatigue and bloody stool. Endoscopic examination showed an ulcerated lesion of the lower rectum. The pathological diagnosis of biopsy specimens from this lesion indicated moderately differentiated...

BACKGROUND Positron emission tomography (PET) with the glucose analogue fludeoxyglucose F 18 uses the increased glucose uptake that is observed in neoplastic cells. It can differentiate between benign and malignant pulmonary lesions in patients with lung tumors. Applications of PET in extracranial head and neck neoplasms have included evaluating patients with unknown primary lesions, detecting ...