• The sympathetic innervation of the vascular tree consists of postganglionic fibers derived from the sympathetic ganglion cells in the cervical, thoracic, and lumbar regions of the sympathetic trunks. In most vascular beds the blood vessels receive their innervation from postganglionic nerves which accompany the main arterial vessels supplying the bed. Information is sparse, however, regarding...

In a most suggestive paper " On the structure, distribution and function of the nerves which innervate the visceral and vascular systems," Gaskell (I) drew attention to the fact that physiological differences observed in peripheral nerves are bound up with morphological differences, so that groups of nerves of the same function can be grouped under the same morphological laws of structure and d...

Background: Right ventricular outflow tract ventricular tachycardia (VT) and ventricular premature complexes (VPCs) are characterized as benign in entity with ECG morphology showing LBBB pattern and inferior axis. Pathogenic mechanisms in the genesis of RVOT VT/VPC remain largely unknown. We aimed to investigate the neural mechanism in RVOT VT/VPC in canine model. Methods: Twelve mongrel dogs (...

Thoracic splanchnic nerves conduct pain sensation from the abdominal organs around the celiac ganglion. Splanchnicectomy is the procedure used mainly for the control of intractable visceral pain. Forty-six human posterior thoracic walls were dissected. The formation pattern, course, and incidence of communication of the thoracic splanchnic nerves were investigated. The greater splanchnic nerves...

The anatomy of the autonomic sympathetic vasomotor nerve supply of bone was studied in rabbits by methods of histochemistry, and fluorescent and electron microscopy. Our observations show that the intraosseous vessels are richly supplied by adrenergic nerves. The large primary nerves are located on or about the surface of the vessel; the medium sized secondary nerves spiral around the long axis...

BACKGROUND Reuptake of norepinephrine by cardiac sympathetic nerves before and during two levels of electrical stimulation of the left ansa subclavia was estimated in anesthetized dogs from the cardiac production of dihydroxyphenylglycol (DHPG), the intraneuronal metabolite of norepinephrine. METHODS AND RESULTS The method depended on the effects of neuronal uptake blockade with desipramine o...

Frequency-domain analyses were used to determine the effect of heat stress on the relationships between the discharge bursts of sympathetic nerve pairs and sympathetic and phrenic nerve pairs in chloralose-anesthetized rats. Sympathetic nerve discharge (SND) was recorded from the renal, splanchnic, splenic, and lumbar nerves during increases in core body temperature (Tc) from 38 to 41.4 ± 0.3°C...

• The sympathetic innervation of the vascular tree consists of postganglionic fibers derived from the sympathetic ganglion cells in the cervical, thoracic, and lumbar regions of the sympathetic trunks. In most vascular beds the blood vessels receive their innervation from postganglionic nerves which accompany the main arterial vessels supplying the bed. Information is sparse, however, regarding...

Increased sympathetic nervous system activity contributes to deoxycorticosterone acetate (DOCA)-salt hypertension in rats. ATP and norepinephrine (NE) are coreleased from perivascular sympathetic nerves. NE acts at prejunctional α2-adrenergic receptors (α2ARs) to inhibit NE release, and α2AR function is impaired in DOCA-salt rats. Adenosine, an enzymatic ATP degradation product, acts at prejunc...

To determine if acute stress activates pancreatic noradrenergic nerves, pancreatic norepinephrine (NE) output (spillover) was measured in halothane-anesthetized dogs. Central neuroglucopenia, induced by intravenous 2-deoxy-D-glucose (12-DGJ 600 mg/kg + 13.5 mg/kg-' per min') increased pancreatic NE output from a baseline of 380±100 to 1,490±340 pg/min (A = +1,110±290 pg/min, P < 0.01). Surgical...