Stretching the atria in anesthetized dogs produces reflex changes in heart rate, and in cardiac and renal sympathetic nerve activity. Anemic decerebration, cord transection at C4-C5, and severance of vagal or sympathetic cardiac nerves was done to identify the pathways and centers essential for these reflexes. Stretching the right atrium produced an aceleration of the heart and a definite incre...

Neuropeptide Y (NPY) is stored with norepinephrine in sympathetic nerves throughout the cardiovascular system and is released during activation of the sympathetic nervous system in humans and other animals. After stimulation of the cardiac sympathetic nerves in anesthetized dogs, the action of the vagus nerve on heart rate is attenuated for a prolonged period. This attenuation of cardiac vagal ...

BACKGROUND Stimuli arousing sympathetic activity can increase ratings of clinical pain in patients with complex regional pain syndrome (CRPS). OBJECTIVE To determine whether the increase in pain is mediated by peripheral sympathetic activity. METHODS The effect of sympathetic ganglion blockade on pain evoked by a startle stimulus and cooling the forehead was investigated in 36 CRPS patients...

Resting vascular sympathetic outflow is significantly increased during and beyond exposure to acute hypoxia without a parallel increase in either resistance or pressure. This uncoupling may indicate a reduction in the ability of sympathetic outflow to effect vascular responses (sympathetic transduction). However, the effect of hypoxia on sympathetic transduction has not been explored. We hypoth...

The objective: was to evaluate the effectiveness of various anesthesia options for laparoscopic hysterectomy, including low-opioid (LOA) and opioid-free (OFA) by studying dynamics heart rate variability (HRV) indicators.Materials methods. 102 patients were randomly assigned 3 groups: 37 who received standard opioid (control group), 33 women LOA group, 32 OFA.Results. Laparoscopic hysterectomy i...

Complex Regional Pain Syndrome (previously known as reflex sympathetic dystrophy, RSD) is a condition presenting with burning, nondermatomal pain associated with hyperhidrosis, intermittent oedema and discolouration and with evidence of mechanical and thermal allodynia. Conventional treatment is with sympathetic blockade produced by local anaesthetic injection around the appropriate sympathetic...

Sympathetic denervation is associated with many diseases. Most cutaneous external monitoring indicators are non-invasive and used widely in clinical medicine. The external monitoring indicators of sympathetic denervation are reviewed to facilitate the clinical diagnosis of sympathetic diseases and the results of sympathectomy. Useful indicators of sympathetic denervation include sweating, warm ...

Cardiovascular function is regulated by a dynamic balance comprised of sympathetic and parasympathetic influences. Sympathetic regulatory centers include the rostra ventrolateral medulla (RVLM) and paraventricular nucleus of hypothalamus (PVN). Pre-sympathetic neurons (PSNs) in these centers project directly to sympathetic preganglionic neurons in the intermediolateral nucleus of the thoracic s...