INTRODUCTION MicroRNAs are small, non coding regulatory molecules containing approximately 21 to 25 nucleotides. They function as controllers of expression at post transcriptional levels of most human protein-coding genes and play an essential role in cell signaling pathways. The objective of the present study is to evaluate the expression profile of the following micro-RNAs: miR-10b, miR-17, m...

BACKGROUND Interleukin (IL)-23 and IL-27 are two IL-12-related cytokines which their function may dramatically influence the inflammatory response to tumor development. IL-12 and IL-27 seem to have antagonistic roles with IL-23 in tumor site. In this study, IL-23 and IL-27 mRNA expressions were analyzed in peripheral blood of patients with breast cancer and healthy volunteers using quantitative...

the aim of this paper is to introduce $(l,m)$-fuzzy closurestructure where $l$ and $m$ are strictly two-sided, commutativequantales. firstly, we define $(l,m)$-fuzzy closure spaces and getsome relations between $(l,m)$-double fuzzy topological spaces and$(l,m)$-fuzzy closure spaces. then, we introduce initial$(l,m)$-fuzzy closure structures and we prove that the category$(l,m)$-{bf fc} of $(l,m...

We study umbilic (space-like) submanifolds of pseudo-Riemannian space forms, then define totally semi-umbilic space-like submanifold of pseudo Euclidean space and relate this notion to umbilicity. Finally we give characterization of total semi-umbilicity for space-like submanifolds contained in pseudo sphere or pseudo hyperbolic space or the light cone.A pseudo-Riemannian submanifold M in (a...

Introduction: One of the most common problems we confront in orthodontic therapy is periodontal diseases. Initial factor which causes these diseases is colonization of anaerobic microorganisms in subgingival plaque. Technically, local environmental changes related to orthodontic band and brackets may influence the bacterial species in periodontal plaque. However, it seems necessary to assess va...

background: while various radiographic parameters and application of manual/gravity stress have been proposed to elucidate instability for weber b fibula fractures, the prognostic capability of these modalities remains unclear. determination of anatomic positioning of the mortise is paramount. we propose a novel view, the gravity reduction view (grv), which helps elucidate non-anatomic position...

in this paper, we use petrov-galerkin elements such as continuous and discontinuous lagrange-type k-0 elements and hermite-type 3-1 elements to find an approximate solution for linear fredholm integro-differential equations on $[0,1]$. also we show the efficiency of this method by some numerical examples