نتایج جستجو برای: suvorexant

تعداد نتایج: 122  

Journal: :Annals of internal medicine 2016
Timothy J Wilt Roderick MacDonald Michelle Brasure Carin M Olson Maureen Carlyle Erika Fuchs Imran S Khawaja Susan Diem Erin Koffel Jeannine Ouellette Mary Butler Robert L Kane

BACKGROUND Pharmacologic interventions are often prescribed for insomnia disorder. PURPOSE To assess the benefits, harms, and comparative effectiveness of pharmacologic treatments for adults with insomnia disorder. DATA SOURCES Several electronic databases (2004-September 2015), reference lists, and U.S. Food and Drug Administration (FDA) documents. STUDY SELECTION 35 randomized, controll...

Journal: :IUPHAR/BPS guide to pharmacology CITE 2023

Orexin receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on [43]) are activated endogenous polypeptides orexin-A and orexin-B (also known hypocretin-1 -2; 33 28 aa) derived from a common precursor, preproorexin or orexin proteolytic cleavage some typical peptide modifications [117]. signaling has been associated with regulation of sleep wakefulness, reward addiction, appetite feed...

2015
Gregory M. Asnis Manju Thomas Margaret A. Henderson Kenji Hashimoto

Insomnia is a prevalent disorder with deleterious effects such as decreased quality of life, and a predisposition to a number of psychiatric disorders. Fortunately, numerous approved hypnotic treatments are available. This report reviews the state of the art of pharmacotherapy with a reference to cognitive behavioral therapy for insomnia (CBT-I) as well. It provides the clinician with a guide t...

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