Herein we report a rapid and sensitive surface Plasmon resonance (SPR) biosensor to detect progesterone (P4), a model analyte of small molecules. A terthiophene scaffold with an oligoethylene glycol (OEG) linker is used as an anchor for the P4-ovalbumin (OVA) immobilization on gold to form a stable, regenerable SPR surface. Subsequently, inhibition SPR immunoassays based on this terthiophene/OV...

The refractive index sensing characteristics of the side-polished photonic crystal fiber (PCF) surface plasmon resonance (SPR) sensor are detailed investigated in this paper. We used the finite element method (FEM) to study the influences of the side-polished depth, air hole size, lattice constant, and the refractive index (RI) of the PCF material on sensing performance. The simulation results ...

A graphene-based long-period fiber grating (LPFG) surface plasmon resonance (SPR) sensor is proposed. A monolayer of graphene is coated onto the Ag film surface of the LPFG SPR sensor, which increases the intensity of the evanescent field on the surface of the fiber and thereby enhances the interaction between the SPR wave and molecules. Such features significantly improve the sensitivity of th...

Si-based surface plasmon resonance (SPR) in the Kretschmann-Raether geometry is considered as a platform for the optical measurement of high refractive index films. The implementation of the SPR effect becomes possible due to the relatively high index of refraction of Si compared to most materials. As examples we study the SPR responses for some important semiconductor-based films, including la...

A plasmon waveguide resonance (PWR) sensor is designed, fabricated, and tested for self-referenced biosensing. The PWR sensor is able to support two different polarizations, TM and TE. The TM polarization has a large sensitivity to variations in the background refractive index while the TE polarization is more sensitive to the surface properties. The ability of the PWR sensor to simultaneously ...

The effect of the Goos-Hanchen (GH) angular shift for a visible light beam under excitation surface plasmon resonance (SPR) in metal subwavelength grating has been investigated. Extremely large GH shifts have demonstrated with an optimal depth. high sensitivity shape transformation and to change angle incidence near SPR shown by rigorous electromagnetic simulation experimentally. focusing refle...

Nanophotonic technique has been attracting much attention in applications of nano-bio-chemical sensing and energy conversion of solar energy harvesting and enhanced energy transfer. One approach for nano-bio-chemical sensing is surface plasmon resonance (SPR) imaging, which can detect the material properties, such as density, ion concentration, temperature, and effective refractive index in hig...

In this paper, we describe the detection of bacterial cell-extracted 16S ribosomal RNA (rRNA) using an emerging technology, surface plasmon resonance (SPR) imaging of DNA arrays. Surface plasmon resonance enables detection of molecular interactions on surfaces in response to changes in the index of refraction, therefore eliminating the need for a fluorescent or radioactive label. A variation of...