A reverse-phase high performance liquid-chromatography (h.p.l.c.) protocol has been developed, whereby all the major known posterior-pituitary components that are derived from the processing of pro-oxytocin and pro-vasopressin can be separated one from another. Thus, in a single chromatographic step, it has been possible to separate vasopressin (VP), oxytocin (OT), oxytocin-neurophysin (rOT-Np)...

Arginine vasopressin-immunoreactive (AVP-ir) neurons in the bed nucleus of stria terminalis (BST) and medial amygdaloid nucleus are very responsive to gonadal hormones. After gonadectomy, these neurons lose their AVP immunoreactivity and stop expressing AVP mRNA. Testosterone treatment reverses these changes, acting via androgen as well as estrogen receptor-mediated mechanisms. Although AVP-ir ...

The article reviews the results of studies morphofunctional state neurons supraoptic nuclei rat hypothalamus under conditions different duration light regime. Under standard regime in rats, a diurnal rhythm activity nucleus with maximum during daytime (before 2 p.m.) is recorded.
 In animals subjected to prolonged exposure, more pronounced changes at a.m. than p.m. were established. Thus, ...

Immunohistochemical techniques were employed to examine the distribution of RNA-binding proteins A2 and B1 in the rat forebrain. Intense A2 and B1 immunolabeling were observed in the nucleoplasm of the neurons in the cerebral cortices, hippocampal formation, olfactory regions, caudate-putamen as well as the supraoptic nucleus of hypothalamus. In contrast, within the bed nucleus of the stria ter...