MicroRNAs (miRNAs) are single-stranded RNA molecules which regulate gene expression at the post-transcriptional level and several miRNAs have been found to be associated with some types of cancer. We sought to identify the expression and involvement of miRNAs in supraglottic carcinoma tissues compared with normal tissues and to determine whether miRNA expression is predictive of disease. Unsupe...

We read with interest the randomized clinical trial by Joo et al. (1) of difficult airway management, in which they compared the merits of inserting the intubating laryngeal mask airway (ILMA) under general anesthesia with awake fiberoptic intubation (AFOI). Joo et al. (1) rightly point out that the ILMA can be used as the sole airway without tracheal intubation. Because a clear airway had been...

A retrospective, longitudinal study of 1,616 patients with primary laryngeal squamous cell carcinoma (LSCC) at a single center in Norway during 1983-2010 was undertaken to investigate overall survival, disease specific survival, disease-free survival, prognostic factors for overall survival, and impact of recurrence among all-stage laryngeal cancer patients over 15 years' follow-up. The prognos...

To the Editor-It was with great interest that I read Dr. Larson's description of "the best treatment" for laryngospasm.' I am not only familiar with the said maneuver, hut have had the opportunity to use it on multiple occasions. In my experience it only works in the semiconscious patient with supraglottic obstruction that is unrelieved by simple airway support measures. I believe that it works...

Supraglottic adenoid cystic carcinoma (ACC) is extremely rare and may be misdiagnosed as laryngeal amyloidosis. The present report describes a case of supraglottic ACC, which went unrecognized until histopathological examination of the neoplasm 18 months after the first presentation. The present patient presented with progressive hoarseness for half a year and initially required partial resecti...

OBJECTIVE To study epidemiology, risk factors and overall survival rate of patients with laryngeal cancer. MATERIAL AND METHOD A chart review of the patients diagnosed with laryngeal cancer in Songklanagarind Hospital over the past 10 years was performed. RESULTS Two hundred eighty nine patient cases were reviewed, in which 106 patients were diagnosed with supraglottic cancer 180 with glott...

OBJECTIVES/HYPOTHESIS The objective of this prospective study was to confirm the validity of transoral robotic supraglottic partial laryngectomy as a conservation surgery for treating supraglottic cancer. STUDY DESIGN Prospective case study. METHODS Between December 2009 and November 2011, 16 patients were enrolled in this study. Acoustic waveform analysis was conducted and Voice Handicap I...

OBJECTIVES/HYPOTHESIS The present study aims to evaluate the degree of anterior-posterior and medial supraglottic laryngeal compression in healthy singers of different voice classifications while singing different pitches, loudness, and phonatory tasks. STUDY DESIGN Prospective study. METHODS Thirty-six classically trained singers (11 sopranos, 11 mezzo-sopranos, six tenors, and eight barit...