BACKGROUND postoperative sore throat is the commonest complication after endotracheal intubation. The efficacy of intravenous non-steroidal anti-inflammatory drugs in alleviating postoperative sore throat has not been investigated. OBJECTIVE To evaluate the effect of intravenous diclofenac sodium on the occurrence and severity of postoperative sore throat. METHODS 42 in-patients scheduled f...

Background and Aims: Trans-rectal ultrasound guided prostate biopsy (TRUS) remains the gold standard to diagnose patients with prostate cancer. The purpose of this study is to prospectively evaluate the efficacy of diclofenac suppository versus diclofenac patch as compared to placebo, on pain reduction during prostate biopsy. Methods: A prospective, randomized, single-blind, placebo controlled ...

OBJECTIVE The aim of this study was to compare the postoperative analgesic effects of preoperative intravenous (i.v.) paracetamol, diclofenac sodium and lornoxicam (nonsteroidal anti-inflammatory drugs). SUBJECTS AND METHODS Sixty patients with impacted third molar who underwent surgical removal were randomly allocated into three groups: group P (n = 20), group D (n = 20) and group L (n = 20)...

BACKGROUND Tonsillectomy is a common procedure causing considerable postoperative pain. Postoperative pain intensity of 60 - 70 in the scale of visual analog scale (VAS) has been reported up to 3 - 4 days which could continue until 11 days after the surgery. OBJECTIVES The current study aimed to compare the analgesic effect of gabapentin and diclofenac on pain after tonsillectomy with the con...

OBJECTIVE To compare the opioid sparing effect of meloxicam, diclofenac, and placebo after abdominal hysterectomy. METHODS This study was conducted at the Riyadh Military Hospital, Riyadh, Kingdom of Saudi Arabia from February 2004 to November 2006. Women of American Society of Anesthesiologist's classification I or II of ages 25-60 years scheduled for abdominal hysterectomy were included. Th...

BACKGROUND Postoperative pain is considered as a reason of patient's delay in discharge and disability aggravation. Therefore, multimodal approaches have been suggested in order to mitigate pain and decrease postoperative side effects. OBJECTIVES The aim of this study was to evaluate analgesic effect of a single dose injection of dexamethasone on reducing postoperative pain in laparoscopic ch...

Recent studies have demonstrated that intranasal is comparable to intravenous opioid titration in its pain-relieving effect. In these studies, however, the intranasal opioid titration was performed by the investigator, and the treatment period was two hours or less. The purpose of this randomized, prospective study was to investigate whether intranasal opioid administration by the patients them...

Objective: While the non-steroidal anti-inflammatory drugs (NSAIDs) represent an important option for the management of acute postoperative pain, their use can be limited due to potential safety concerns, including bleeding risks. This study examined the bleeding-related safety of injectable diclofenac formulated with hydroxypropyl-β-cyclodextrin (HPβCD-diclofenac) when used for postoperative p...

Aim: to prospectively evaluate degree of pain during transrectal ultrasound-guided prostate biopsy after receiving analgesics treatment of oral morphine sulphate compared to suppository sodium diclofenac. Methods: the study group comprised 60 consecutive men subjects (median age 67.8 years) undergoing transrectal prostate biopsy. They were randomized into two groups; group 1 received oral analg...