A new study links individual differences in unconsciously triggered motor control to variability in GABA neurotransmitter concentration in the supplementary motor area of the human brain.

[PDF] [Full Text] [Abstract] , May 5, 2004; 24 (18): 4453-4459. J. Neurosci. D. Lee Behavioral Context and Coherent Oscillations in the Supplementary Motor Area [PDF] [Full Text] [Abstract] , December 1, 2004; 92 (6): 3482-3499. J Neurophysiol E. Hoshi and J. Tanji Motor Areas: From Information Retrieval to Motor Planning and Execution Differential Roles of Neuronal Activity in the Suppleme...

Clower, William T. and Garrett E. Alexander. Movement semovements precede, or follow, X . Here we present evidence quence-related activity reflecting numerical order of components that the numerical order of specific components may also in supplementary and presupplementary motor areas. J. Neurobe represented by movement sequence-related activity of physiol. 80: 1562–1566, 1998. The supplementa...

Juvenile myoclonic epilepsy is the most frequent idiopathic generalized epilepsy syndrome. It is characterized by predominant myoclonic jerks of upper limbs, often provoked by cognitive activities, and typically responsive to treatment with sodium valproate. Neurophysiological, neuropsychological and imaging studies in juvenile myoclonic epilepsy have consistently pointed towards subtle abnorma...

Findings from studies using electrical stimulation of cortex, recording from single neurons in awake animals, and measuring regional cerebral blood flow in humans have revealed some specific motor functions for several cerebral cortical areas. These areas include primary motor cortex, supplementary motor area, premotor area, parietal areas 5 and 7, and prefrontal area. Execution of movement is ...

While a tumour in or abutting primary motor cortex leads to motor weakness, how tumours elsewhere in the frontal or parietal lobes affect functional connectivity in a weak patient is less clear. We hypothesized that diminished functional connectivity in a distributed network of motor centres would correlate with motor weakness in subjects with brain masses. Furthermore, we hypothesized that int...

We used retrograde transneuronal transport of neurotropic viruses in Cebus monkeys to examine the organization of basal ganglia and cerebellar projections to two cortical areas on the medial wall of the hemisphere, the supplementary motor area (SMA) and the pre-SMA. We found that both of these cortical areas are the targets of disynaptic projections from the dentate nucleus of the cerebellum an...