We have utilized the copper-catalyzed azide-alkyne reaction to form a dense monolayer of oligonucleotides on a superparamagnetic nanoparticle core. These particles exhibit the canonical properties of materials densely functionalized with DNA, which can be controlled by modulating the density of oligonucleotides on the surface of the particles. Furthermore, like their Au analogues, these particl...

The aggregation of superparamagnetic iron oxide (SPIO) nanoparticles decreases the transverse nuclear magnetic resonance (NMR) relaxation time T2CP of adjacent water molecules measured by a Carr-Purcell-Meiboom-Gill (CPMG) pulse-echo sequence. This effect is commonly used to measure the concentrations of a variety of small molecules. We perform extensive Monte Carlo simulations of water diffusi...

The antigen-capturing activity of antibody-coated nanoparticles is very important for affinity-based bioanalytical tools. In this paper, a comprehensive study is reported of the antigen-capturing activity of antibodies that are nondirectionally immobilized on a nanoparticle surface. Superparamagnetic nanoparticles (500 nm) were covalently functionalized with different quantities of monoclonal a...

Steric barriers such as collagen I sharply limit interstitial delivery of macromolecular and nanoparticle (NP) based therapeutic agents. Collagenase-linked superparamagnetic NPs overcame these barriers and moved through in vitro extracellular matrix (ECM) at 90 microm h(-1), a rate similar to invasive cells, under the influence of a magnetic field. NP migration in ECM diminished linearly over 5...

1 DOI: 10.1002/smll.200800353 Real-time Tracking of Superparamagnetic Nanoparticle Self-assembling P. Siffalovic, E. Majkova, L. Chitu, M. Jergel, S. Luby, I. Capek, A. Satka, A. Timmann, and S. V. Roth* [*] Dr. P. Siffalovic, Dr. E. Majkova, MSc. L. Chitu, Dr. M. Jergel, Prof. S. Luby Institute of Physics, Slovak Academy of Sciences Dubravska cesta 9, 84511 Bratislava (Slovakia) E-mail: peter....

We introduce a method to improve the detection sensitivity for the magnetization M of superparamagnetic nanoparticles (MNP). The M response of MNP to an applied magnetic field H (M-H characteristics) could be divided into a linear region and a saturation region, which are separated at a transition point H(k). When applying an excitation magnetic field (H(ac)) with a frequency ω0 and an addition...

Abstract The magnetic nanoparticle assisted photocatalytic oxidation-reduction is an effective method to remove and detoxify the organic dyes heavy metal ions present in industrial wastewater. In study, degradation of Methyl Orange(MO) dye Cr(VI) presence cobalt ferrite (CoFe 2 O 4 ) superparamagnetic photocatalysts under visible light illumination are investigated as a function wide range pH s...

Magnetic nanoparticles of magnetite with a size ~8 nm synthesized different type coating were studied by ferromagnetic resonance in the temperature range from 7 to 300 K. The features experimental dependences parameters curve (the magnitude resonant field, line width and intensity) their approximation allowed us estimate values characteristic temperatures. Firstly, value Vervey dependence its o...