With the incidence of nonmelanoma skin cancer on the rise, current prevention methods, such as the use of sunscreens, have yet to prove adequate to reverse this trend. There has been considerable interest in identifying compounds that will inhibit or reverse the biochemical changes required for skin cancers to develop, either by pharmacologic intervention or by dietary manipulation. By targetin...

Sunscreens in organ transplant patients Claas Ulrich1, Annette Degen2, Manisha J. Patel3 and Eggert Stockfleth1 1Department of Dermatology, Skin Cancer Center Charité, Universitätsmedizin Charité, Berlin, 2Department of Dermatology and Allergology, Hannover Medical University, Germany and 3Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA Nephrol Dial Tr...

1 This educational resource summarises recent developments in sunscreen research, knowledge, and use. It starts with a review of the Nambour Skin Cancer Prevention Trial, which contributes to the evidence for a protective effect of sunscreen against melanoma. This is followed by consideration of UVA protection, correct application of sunscreen, skin type in sun protection, and compliance with s...

Exposure to UV radiation can cause skin damage; among UV rays UVB are commonly considered to be more important in inducing photoaging and skin cancer; however in recent years some authors have claimed an important role also for UVA that can concur with UVB to damage the skin. UVB rays have a wavelength between 280 and 320 nm and are responsible for immediate skin damage represented by erythema....

Commercial sunscreens may offer some protection from immunosuppression induced by ultraviolet (UV) radiation, but agreement concerning the degree of protection is lacking. Cis-urocanic acid, formed by the photoisomerization of transurocanic acid is considered an important mediator of the cutaneous immunomodulation resulting from exposure to UV radiation. We investigated the effect of sunscreens...