Iron is a ubiquitous constituent of cytochromes, oxygen-binding molecules and a variety of enzymes because of its property to transition from ferric (Fe3+) to ferrous (Fe2+) state, leading to change in the redox potential. However, the same property accounts for free radical injury. In order to overcome harmful effects of iron we investigated the possible protective effect of quercetin (QCT), a...

OBJECTIVE To elucidate potential antioxidant, antidiarrheal, cytotoxic, and antibacterial activities of the ethanol extract of Alocasia indica Schott tuber in different experimental models established in vitro and in vivo. METHODS In vitro antioxidant activity was evaluated by 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging assay. Phenolic content was estimated by using Folin-Ciocalt...

This work aimed at the degradation of synthetic estrogen 17α-ethinyl estradiol (EE2) via a combined photoelectrocatalysis (PEC) and peroxymonosulfate (PMS) process. Pristine TiO2/WO3 photoanodes were fabricated used in this work. The removal 1 mg L−1 EE2 increased from 47.9 % to 88.8 60 min by adding 10 PMS an external bias V. was degraded presence 0.05 M sodium sulfate as electrolyte. rate con...

The sulfate ester of 7V-hydroxy-2-acetamidophenanthrene was prepared and was found to react significantly with methionine, adenosine, and guanosine. The adduci from the methionine reaction was characterized as 1-methylmercapto-2acetamidophenanthrene. The levels of reaction with adenosine and guanosine were comparable, in contrast with the observation that TV-acetoxy-2-acetamidofluorene shows a ...

The acute lung injury resulting from adult respiratory distress syndrome (ARDS) is thought to be largely mediated by activated neutrophils. Because activated neutrophils produce the superoxide radical, which is both bacterial and cytotoxic to host cells, this oxygen-derived free radical is likely responsible for at least part of the neutrophil-mediated lung injury. In a rat model of ARDS result...

The sulfate ester of 7V-hydroxy-2-acetamidophenanthrene was prepared and was found to react significantly with methionine, adenosine, and guanosine. The adduci from the methionine reaction was characterized as 1-methylmercapto-2acetamidophenanthrene. The levels of reaction with adenosine and guanosine were comparable, in contrast with the observation that TV-acetoxy-2-acetamidofluorene shows a ...

Vitamin C (VC) is a well-known antioxidant and strong free radical scavenger. Its antioxidant activity is useful for protection of cellular macromolecules, particularly DNA, from oxidative damage induced by different agents. This study was undertaken to evaluate the optimum level of VC in attenuating the chromosome aberrations (CAs) and DNA damage after iron sulfate (FeSO4) acute administration...

The antioxidant and antimicrobial potential of the ethanolic extract of Pleurotus ostreatus PQMZ91109 mycelium was determined based on inorganic and organic nitrogen sources in the culture medium. The presence of ammonium sulfate resulted in a greater accumulation of bioactive compounds compared with the organic ones. This finding was also confirmed by the low values of the ascertained EC(50) a...

Radical depolymerisation is the method of choice for the depolymerisation of glycosaminoglycans (GAGs), especially when enzymatic depolymerisation cannot be performed due to the lack of suitable enzymes. The established Fenton type free radical depolymerisation generates radicals from a solution of H2O2 in the presence of Cu(2+) or Fe(2+). When applied to dermatan sulfate (DS), the Fenton type ...