Introduction: Molecular hybridization is a synthesis strategy in which new molecules are obtained by linking two drugs or pharmacophoric groups. Skin conditions treatment, such as acne, generally  requires the association of drugs, for instance, sulfacetamide and salicylic acid. The present study aimed to synthesize characterize drug candidate molecular using We also intended further explore ev...

Abstract In this study, magnetic-dispersive solid-phase extraction coupled with ion pair-dispersive liquid–liquid micro-extraction (MSPE-i-DLLME) was used to the pre-concentration and of five sulfonamides residues (sulfadiazine, sulfathiazole, sulfacetamide, sulfamethazine sulfamethoxazole) in animal foodstuffs. The are extracted using magnetic carbon nanocomposite then eluted acetonitrile. DLL...

A number of genetic systems are described which involve the use of the yeast Saccharomyces cerevisiae. The systems may be used to detect the production of aneuploid cells produced during both mitotic and meiotic cell division in the presence of genetically active chemicals. During mitotic cell division, monosomic colonies (2n - 1) may be detected by plating upon selective medium. Increases in s...

Although currently recommended antibiotics for Lyme disease such as doxycycline or amoxicillin cure the majority of the patients, about 10-20% of patients treated for Lyme disease may experience lingering symptoms including fatigue, pain, or joint and muscle aches. Under experimental stress conditions such as starvation or antibiotic exposure, Borrelia burgdorferi can develop round body forms, ...

Raji, A.R. and Norozi, E. 2010. Distribution of external taste buds in walking catfish (Clarias batrachus) and piranha (Serrasalmus nattereri). J. Appl. Anim. Res., 37: 49-52. To determine the distribution of external taste buds (TB), 3 specimen each of the two species of aquarium fishes: Walking catfish (Claris batrachus) and Piranha (Serrasalmus nattereri), were studied. In walking catfish TB...

Cooke, Davenport, and Goodman4 have shown that five sulfonamide drugs are secreted in the gastric juice. When the concentration ratio is defined as the concentration in the gastric juice divided by the concentration in the plasma it is found that the average concentration ratios of sulfanilamide and sulfapyridine are 2.6 and 3.2 respectively. The average concentration ratios of sulfathiazole, s...

1045 n FEATURED CLINICAL INVESTIGATION ARTICLE. Phase II Study of a Radiotherapy Total Dose Increase in Hypoxic Lesions Identified by F-Misonidazole PET/CT in Patients with Non–Small Cell Lung Carcinoma (RTEP5 Study) Pierre Vera, Sébastien Thureau, Philippe Chaumet-Riffaud, Romain Modzelewski, Pierre Bohn, Maximilien Vermandel, Sébastien Hapdey, Amandine Pallardy, Marc-André Mahé, Marie Lacombe...

Correspondence MEDIALJOUH How much easier it would be if platelet stickiness were expressed as the percentage of sticky platelets rather than as the percentage of non-sticky platelets, and how much more logical. That is: Platelet stickiness (%)= (Original Count minus Second Count) x 100 Original Count With this simple transformation a high value would indicate a high degree of sticki-ness, and ...