نتایج جستجو برای: suicide gene
تعداد نتایج: 1164769 فیلتر نتایج به سال:
Colorectal cancer is the most common cancer in both men and women and the second most common cause of cancer-related deaths. Suicide gene-based therapy with suicide gene-transduced mesenchymal stem cells (MSCs) is a promising therapeutic strategy. A tetracycline-controlled Tet-On inducible system used to regulate gene expression may be a useful tool for gene-based therapies. The aim of this stu...
Bacteria are highly skilled at biological warfare. They have a range of weapons at their disposal: everything from secreted toxins to camouflage. Many bacteria can even make use of what’s known as a toxin– antitoxin system to program their own individual suicide in support of the population’s survival. In this system, a bacterial toxin lies dormant within the bacterium, wrapped up and prevented...
We have developed very efficient suicide functions for biological containment based on the lethal Escherichia coli relF gene. The suicide functions are placed in duplicate within a plasmid and arranged to prevent inactivation by deletion, recombination, and insertional inactivation. The efficiency of this concept was tested in a plasmid containment system that prevents transfer of plasmids to w...
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