Dear Sir, Sudden Infant Death Syndrome or SIDS remains an important cause of mortality in infants. The 2011 publication of Siren and Siren (1) and the subsequent letter to theeditor (2) focusoncriticaldiaphragm failure as a possible cause and provide plausible evidence. However, these articles do not explore the metabolic basis for this critical diaphragm failure. Several authors, includingAubi...

We report the first patient with pathologically proven leukoencephalopathy associated with hypophosphatemia. A 61-year-old woman had repetitive episodes of decreased consciousness with pontine and pallidal lesions and extensive leukoencephalopathy on MRI, later found to be associated with hypophosphatemia. Although hypophosphatemia has been linked to central pontine and extrapontine myelinolysi...

Hypophosphatemia is common in hospitalized patients and occurs under a variety of circumstances other than parathyroid hormone excess. Charts of 100 inpatients with hypophosphatemia were reviewed and the patients divided into five groups on the basis of serum phosphate level: 18, 2.1 to 2.4 mg/dL; 49, 1.6 to 2.0 mg/dL; 20, 1.1 to 1.5 mg/dL; 12, 0.6 to 1.0 mg/dL; 1, 0.1 to 0.5 mg/dL. The effect ...

Chronic kidney disease-mineral bone disorder (CKD-MBD) after transplantation is a mix of pre-existing disorders and new alterations. The final consequences are reflected fundamentally as abnormal mineral metabolism (hypercalcemia, hypophosphatemia) alterations [high or low turnover disease (as fibrous osteitis adynamic disease), an eventual compromise mineralization, decrease density fractures]...