Nitrile N-oxides are useful reagents and crosslinkers for catalyst- byproduct-free 1,3-dipolar cycloaddition reactions. The stability of nitrile can be enhanced by introducing bulky substituents, whereas their reactivity decreases concomitantly. Herein, an isolatable aliphatic ditopic N-oxide was synthesized applied to catalyst-free crosslinking unsaturated bond-containing polymers. By decreasi...

The reaction of 17,17-dichloro-androst-16(E)-chloromethylene with secondary amine base afforded substitution products exocyclic D-ring ketones, in contrast to the alkaline which cleaved steroidal des-D formyl alkyne. alkyne was employed prepare annulated isoxazolo steroid via 1,3-dipolar nitrile oxide cycloaddition reaction.

New triazine-based tricarboxylic acid linkers were prepared as elongated relatives of triazinetribenzoic acid (TATB). Additionally, functional groups (NO2, NH2, OMe, OH) were introduced for potential post-synthetic modification (PSM) of MOFs. Functionalized tris(4-bromoaryl)triazine "cores" (3a,3b) were obtained by unsymmetric trimerization mixing one equivalent of an acid chloride (OMe or NO2 ...

A series of per-O-benzoylated 5-beta-D-glucopyranosyl-2-substituted-1,3,4-oxadiazoles was prepared by acylation of the corresponding 5-(beta-D-glucopyranosyl)tetrazole. As an alternative, oxidation of 2,6-anhydro-aldose benzoylhydrazones by iodobenzene I,I-diacetate afforded the same oxadiazoles. 1,3-Dipolar cycloaddition of nitrile oxides to per-O-benzoylated beta-D-glucopyranosyl cyanide gave...

In the title ferrocene derivative, [Fe(C5H5)(C9H8NO)], the dihedral angle between the ene-nitrile group and the substituted cyclo-penta-dienyl ring is 71.2 (1)°. The cyclopentadienyl rings of the ferrocene moiety are arranged in an eclipsed conformation. The hy-droxy group, and the corresponding methine H atom, are disordered over two sets of sites with site-occupancy factors of 0.744 (4) and 0...

The synthesis of new vicinal diamines based on aziridine and azetidine cores as well as the comparison of their catalytic activities as ligand in the Suzuki-Miyaura coupling reaction are described in this communication. The synthesis of threeand four-membered ring heterocycles substituted by a methylamine pendant arm is detailed from the parent nitrile derivatives. Complexation to palladium und...